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  4. Recombinant Mouse Uncharacterized protein C17orf96 homolog

Recombinant Mouse Uncharacterized protein C17orf96 homolog

  • 中文名称：
    小鼠Epop重组蛋白
  • 货号：
    CSB-YP749253MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Epop重组蛋白
  • 货号：
    CSB-EP749253MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Epop重组蛋白
  • 货号：
    CSB-EP749253MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Epop重组蛋白
  • 货号：
    CSB-BP749253MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Epop重组蛋白
  • 货号：
    CSB-MP749253MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Epop
  • Uniprot No.：
  • 别名：
    Epop; E13Elongin BC and Polycomb repressive complex 2-associated protein; Embryonic stem cell-specific PRC2 subunit p48; ES cell-specific PRC2 subunit p48; esPRC2p48
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-369
  • 氨基酸序列
    METLCPPPRL AVPASPRGSP CSPTPLKPRR GTPEFSPLCL RALAFCALAK PRPSSLGLGP GELAPRTPVL LGPPASPCTG GWAADGLKHL GGQAGRPSDV SSPAREDADV AVCPGGGEEE EGGGGFPHFG AGSCAPPGRC PAPLRPQDSP TNPAWSPPRP ARGLDAASSP PLEPGSPPPS PPAGLSPEPA PSEQPVPASE APGGGDPAPT APEAPALSPS TADAAPDPPR DLRQEHFNRL IRRSKLWCYA KGFALDTPSL RRGPERPAAK ARGAAKKRRR PAPPPPSVQP RRPVPTLPTS STFSLLDCFP CPPALVVEEN GDLGPASSLR LQGDAKPPPA HPLWKWQMGG PAVPEPPGLK SWWVNLEEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Scaffold protein that serves as a bridging partner between the PRC2/EZH2 complex and the elongin BC complex: required to fine-tune the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells (ESCs). Plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression at PcG target genes: acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EZH2 complex. Interaction with USP7 promotes deubiquitination of H2B at promoter sites. Acts as a regulator of neuronal differentiation.
  • 基因功能参考文献：
    1. Results demonstrated that E130012A19Rik (E13), is a protein-coding gene implicated in regulating the commitment towards the different neuronal subtypes and glia cells. PMID: 23180766
    2. these studies identify JARID2, MTF2, and esPRC2p48 as important regulatory subunits of PRC2 in ES cells and reveal critical functions of these subunits. PMID: 21732481
  • 亚细胞定位：
    Nucleus. Chromosome.
  • 组织特异性：
    Highly expressed in embryonic stem cells (ESCs) during embryogenesis and in the adult brain.
  • 数据库链接：

    KEGG: mmu:103551

    STRING: 10090.ENSMUSP00000051211

    UniGene: Mm.24506