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  4. Recombinant Mouse Uncharacterized protein KIAA1737 (Kiaa1737)

Recombinant Mouse Uncharacterized protein KIAA1737 (Kiaa1737)

  • 中文名称：
    Recombinant Mouse Uncharacterized protein KIAA1737(Kiaa1737),Yeast
  • 货号：
    CSB-YP819160MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Uncharacterized protein KIAA1737(Kiaa1737),Yeast
  • 货号：
    CSB-EP819160MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Uncharacterized protein KIAA1737(Kiaa1737),Yeast
  • 货号：
    CSB-EP819160MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Uncharacterized protein KIAA1737(Kiaa1737),Yeast
  • 货号：
    CSB-BP819160MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Uncharacterized protein KIAA1737(Kiaa1737),Yeast
  • 货号：
    CSB-MP819160MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cipc
  • Uniprot No.：
  • 别名：
    Cipc; Kiaa1737CLOCK-interacting pacemaker; CLOCK-interacting circadian protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-432
  • 氨基酸序列
    MRLLTRRAGH GAATLALRVI HMQRVPVLRL PAILDMERKI PSRESPRRLS AKPGRGTEMK KLARPLGVVA ADSDKDSGFS DGSSECLSSA EQMESEDMLS ALGCKREDKR RQPSKAADTA LPTLPPMVVM KSVLVKQGSS SSQLQSWTVQ PSFEVISAQP QLFVLHPPVP SPVSSCQTGE KKSESRNYLP ILNSYTKIAP HPGKRGLNSE DRGTSGVSKK LCTERPGPSL SSSEPAKTGR VLSSPSTPAP PSSKLTEDST LQGVPSLGAG GSPQTLQPVS SSHVAKAPSL TLASPASPVC ASDSTLHGLE SSSPLSPLSA SYTSPLWAAE HLCRSPDIFS EQRQNKHRRF QNTLVVLHKS GLLEITLKTK ELIRQNQATQ AELDQLKEQT QMFIEATKSR APQAWAKLQA SLTSGSSHSG SDLDTLSDHP DV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock.
  • 基因功能参考文献：
    1. mRNA expression profiles of core clock genes in the liver of Cipc (-/-) mice showed no significant differences from that in wild-type mice except for Per1 PMID: 25862660
  • 亚细胞定位：
    Nucleus. Cytoplasm, cytosol.
  • 组织特异性：
    Expressed in the heart, kidney and liver and shows a circadian oscillation in these tissues with a peak at circadian time 14 hours (at protein level). Expressed in the brain, including the suprachiasmatic nucleus (SCN) of the brain, and in multiple periph
  • 数据库链接：

    KEGG: mmu:217732

    STRING: 10090.ENSMUSP00000038630

    UniGene: Mm.22337