Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Zinc finger protein with KRAB and SCAN domains 3 (Zkscan3)

Recombinant Mouse Zinc finger protein with KRAB and SCAN domains 3 (Zkscan3)

  • 中文名称：
    小鼠Zkscan3重组蛋白
  • 货号：
    CSB-YP820992MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Zkscan3重组蛋白
  • 货号：
    CSB-EP820992MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Zkscan3重组蛋白
  • 货号：
    CSB-EP820992MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Zkscan3重组蛋白
  • 货号：
    CSB-BP820992MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Zkscan3重组蛋白
  • 货号：
    CSB-MP820992MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Zkscan3
  • Uniprot No.：
  • 别名：
    Zkscan3; Skz1; Zfp306; Zfp307; Zfp47Zinc finger protein with KRAB and SCAN domains 3; SCAN-KRAB-zinc finger protein; Zinc finger protein 306; Zinc finger protein 307; Zinc finger protein 47 homolog; Zf47; Zfp-47
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-553
  • 氨基酸序列
    MARESRESTT LDSHSAEDQM ELLVIKVEQE ESSPLAEETS WLGSPGPDRS RQRFRAFRYP EAAGPRQALS RLRELCRQWL RPDMHSKEQI LELLVLEQFL TILPGELQAW VREQHPDSGE EVVALLEYLD RQLDDTPPQV PDDDDGQELL CSKAVLLTSA QGSESSQMEP VEPLLKQESL GSLPSEVRVT HVGHCGEDGV TATRLTSELQ GLLKMEDVAP VLSPRWTEQD SSQMNLYKDG MQEHSGSLVS LDQDMQTKVR DLPRAEEYRD QKPEQTVCFL GEDTVPIPTG AEASEQEGKL QAAQKSATGT RRFYCRECGK SFAQSSGLSK HKRIHTGLKP YECEECGKAF IGSSALIIHQ RVHTGEKPYE CEECGKAFSH SSDLIKHQRT HTGEKPYECD DCGKTFTQSC SLLEHHRIHT GEKPYQCNMC PKAFRRSSHL LRHQRTHTGD KDFFVPEPYW ESQSRVESHW ENIETPVSYQ CNDCERSFSR ITSLIEHQKV HTGEKPFECQ TCGKGFTRPS YLIQHQRRHT GKKTSVTVTP AVHSEVGVQL SLN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters.
  • 基因功能参考文献：
    1. ZKSCAN3 regulates the expression of several genes favoring tumor progression including integrin beta 4 and VEGF PMID: 18940803
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
  • 数据库链接：

    KEGG: mmu:72739

    STRING: 10090.ENSMUSP00000068424

    UniGene: Mm.296071