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  4. Recombinant Oryzias latipes Cellular tumor antigen p53 (tp53)

Recombinant Oryzias latipes Cellular tumor antigen p53 (tp53)

  • 货号：
    CSB-YP024077OFH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP024077OFH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP024077OFH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP024077OFH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP024077OFH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    tp53; p53; Cellular tumor antigen p53; Tumor suppressor p53
  • 种属：
    Oryzias latipes (Medaka fish) (Japanese ricefish)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-352
  • 氨基酸序列
    MDPVPDLPES QGSFQELWET VSYPPLETLS LPTVNEPTGS WVATGDMFLL DQDLSGTFDD KIFDIPIEPV PTNEVNPPPT TVPVTTDYPG SYELELRFQK SGTAKSVTST YSETLNKLYC QLAKTSPIEV RVSKEPPKGA ILRATAVYKK TEHVADVVRR CPHHQNEDSV EHRSHLIRVE GSQLAQYFED PYTKRQSVTV PYEPPQPGSE MTTILLSYMC NSSCMGGMNR RPILTILTLE TEGLVLGRRC FEVRICACPG RDRKTEEESR QKTQPKKRKV TPNTSSSKRK KSHSSGEEED NREVFHFEVY GRERYEFLKK INDGLELLEK ESKSKNKDSG MVPSSGKKLK SN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
  • 基因功能参考文献：
    1. p53 is not essential for tissue self-renewal in developing brain. PMID: 26410759
    2. These results suggest that p53 positively regulates neurogenesis via cell proliferation. PMID: 22659737
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    P53 family
  • 数据库链接：

    KEGG: ola:100049321

    STRING: 8090.ENSORLP00000008029

    UniGene: Ola.4812