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tp53

TP53(也被称为p53)是一种转录因子,包含多个功能域,如DNA结合域、转录激活域和核定位信号。在细胞中扮演着监测DNA损伤和维持基因组稳定性的重要角色。当细胞受到损伤或遭受压力时,p53会被激活,促进修复受损的DNA或诱导受损细胞的凋亡。这有助于防止DNA损伤的传播,避免受损细胞的异常增殖,以及防止肿瘤的形成。p53激活的信号通路涉及多种分子和蛋白质的相互作用,其中包括对DNA损伤信号的感知、启动DNA修复和细胞凋亡等途径。p53作为一种肿瘤抑制基因,在细胞中起着关键作用,对于维持基因组稳定性和防止肿瘤的发生具有重要意义。

热销产品

Recombinant Human Cellular tumor antigen p53 (TP53)

验证数据

SDS-PAGE
CSB-EP024077HU-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS
CSB-EP024077HU LC-MS-1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP024077HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TP53.

LC-MS
CSB-EP024077HU LC-MS-2

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP024077HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TP53.


tp53 Antibodies

tp53 for Rattus norvegicus (Rat)

tp53 for Homo sapiens (Human)

tp53 for Mus musculus (Mouse)

tp53 for H

tp53 for H,R,M

tp53 Proteins

tp53 Proteins for Equus caballus (Horse)

tp53 Proteins for Bos taurus (Bovine)

tp53 Proteins for Gallus gallus (Chicken)

tp53 Proteins for Felis catus (Cat) (Felis silvestris catus)

tp53 Proteins for Ovis aries (Sheep)

tp53 Proteins for Macaca mulatta (Rhesus macaque)

tp53 Proteins for Homo sapiens (Human)

tp53 Proteins for Mus musculus (Mouse)

tp53 Proteins for Bos indicus (Zebu)

tp53 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)

tp53 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

tp53 Proteins for Rattus norvegicus (Rat)

tp53 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

tp53 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

tp53 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

tp53 Proteins for Macaca fuscata fuscata (Japanese macaque)

tp53 Proteins for Xenopus laevis (African clawed frog)

tp53 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

tp53 Proteins for Platichthys flesus (European flounder) (Pleuronectes flesus)

tp53 Proteins for Marmota monax (Woodchuck)

tp53 Proteins for Xiphophorus helleri (Green swordtail)

tp53 Proteins for Ictalurus punctatus (Channel catfish)

tp53 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

tp53 Proteins for Equus asinus (Donkey)

tp53 Proteins for Spermophilus beecheyi (Beechey ground squirrel) (Otospermophilus beecheyi)

tp53 Proteins for Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)

tp53 Proteins for Delphinapterus leucas (Beluga whale)

tp53 Proteins for Oryctolagus cuniculus (Rabbit)

tp53 Proteins for Tupaia belangeri (Common tree shrew) (Tupaia glis belangeri)

tp53 Proteins for Sus scrofa (Pig)

tp53 Proteins for Cavia porcellus (Guinea pig)

tp53 Proteins for Barbus barbus (Barbel)

tp53 Proteins for Tetraodon miurus (Congo puffer)

tp53 ELISA Kit

tp53 ELISA Kit for Homo sapiens (Human)