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  4. Recombinant Pig Corticosteroid-binding globulin (Serpina6)

Recombinant Pig Corticosteroid-binding globulin (Serpina6)

  • 中文名称：
    斯克罗法Serpina6重组蛋白
  • 货号：
    CSB-YP872377PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法Serpina6重组蛋白
  • 货号：
    CSB-EP872377PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法Serpina6重组蛋白
  • 货号：
    CSB-EP872377PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法Serpina6重组蛋白
  • 货号：
    CSB-BP872377PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法Serpina6重组蛋白
  • 货号：
    CSB-MP872377PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Serpina6
  • Uniprot No.：
  • 别名：
    Serpina6; Cbg; Corticosteroid-binding globulin; CBG; Serpin A6; Transcortin
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    23-406
  • 氨基酸序列
    KDPDSDLS TRSRHRNLAP NNVDFAFALY KHLVASAPGK DVFLSPVSIS TALAMLSLGA SGYTREQLLQ GLGFNLTETP EAEIHQDFQH LHSLLKGSNI TSEMTMGNAL FLDRSLELLE SFSTGSKHYY GLEALAADFQ DWAGASRQIN EYIKNKTQGK IVDLFLEQDS SAMLILINYI FFKGTWTHSF PPESTREENF YVNETATVKV PMMFQSRAMK YLNDSLLPCQ LVQLEYTGNE TAFFILPVKG EMDTVIAGLS RDTIQRWSKS LIPSQVDLYV PKVSISGAYD LGSILGDMGI VDLLSHPTHF SGITQNALPK MSKVVHKAVL QFDEKGMEAA APTTRGRSLH AAPKPVTVHF NRPFIVMVFD HFTWSSLFLG KIVNLT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
  • 基因功能参考文献：
    1. non-synonymous polymorphisms of SERPINA6, particularly SNPs c.919G>A and c.44G>T/c.622C>T, are associated with cortisol level, HPA axis activity, and carcass and meat quality traits PMID: 25754835
    2. The putative causal amino acid substitution p.Gly307Arg (SNP c.919G>A) associated with meat quality (drip loss) was only detected in European domestic pig breeds, suggesting a very recent mutation that appeared after domestication in Europe. PMID: 21054451
    3. Cbg gene is a key regulator of cortisol levels and obesity susceptibility. PMID: 15087473
    4. Negative relationship exists between plasma cortisol and CBG under conditions of acute stress. PMID: 17613944
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Serpin family
  • 数据库链接：

    KEGG: ssc:396736

    STRING: 9823.ENSSSCP00000002680

    UniGene: Ssc.3831