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  4. Recombinant Pongo abelii Peroxisomal NADH pyrophosphatase NUDT12 (NUDT12)

Recombinant Pongo abelii Peroxisomal NADH pyrophosphatase NUDT12 (NUDT12)

  • 中文名称：
    波戈阿贝利NUDT12重组蛋白
  • 货号：
    CSB-YP719270PYX
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    波戈阿贝利NUDT12重组蛋白
  • 货号：
    CSB-EP719270PYX
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    波戈阿贝利NUDT12重组蛋白
  • 货号：
    CSB-EP719270PYX-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    波戈阿贝利NUDT12重组蛋白
  • 货号：
    CSB-BP719270PYX
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    波戈阿贝利NUDT12重组蛋白
  • 货号：
    CSB-MP719270PYX
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NUDT12
  • Uniprot No.：
  • 别名：
    NUDT12; Peroxisomal NADH pyrophosphatase NUDT12; EC 3.6.1.22; Nucleoside diphosphate-linked moiety X motif 12; Nudix motif 12
  • 种属：
    Pongo abelii (Sumatran orangutan)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-462
  • 氨基酸序列
    MSSVKRTPKQ EIVTQFHCSA AEGDIAKLTG ILSHSPSLLN ETSENGWTAL MYAARNGHPE IVQFLLEKGC DRSIVNKSRQ TALDIAVFWG YKHIANLLAT AKGGKKPWFL TNEVEECENY FSKTLLDRKS EKRNNSDWLL AKESHPATVF ILFSNLNPLV TLGGNKESFQ QPEVRLCQLN YTDIKDYLAQ PEKITLIFLG VELEIKDKLF NYAGEVPREE EDGLVAWFAL GIDPIAAEEF KQRHENCYFL HPPMPALLQL KEKEAGVVAQ ARSVLAWYSR YKFCPTCGNA TKIEEGGYKR VCLKEDCPSL NGVHNTSYPR VDPVVIMQVI HPDGTKCLLG RQKRFPPGMF TCLAGFIEPG ETIEDAVRRE VEEESGVKVG HVQYVACQPW PMPSSLMIGC LALAVSTEIK VDKNEIEDAH WFTREQVLDV LTKGKQQAFF VPPSRAIAHQ LIKHWIRINP NL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Preferentially acts on NAD-capped transcripts in response to nutrient stress. Also acts on free nicotinamide adenine dinucleotide molecules: hydrolyzes NAD(H) into NMN(H) and AMP, and NADPH into NMNH and 2',5'-ADP. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle. Regulates the levels of circadian clock components PER1, PER2, PER3 and CRY2 in the liver.
  • 亚细胞定位：
    Cytoplasm. Peroxisome. Cytoplasmic granule.
  • 蛋白家族：
    Nudix hydrolase family, NudC subfamily
  • 数据库链接：

    KEGG: pon:100172011

    STRING: 9601.ENSPPYP00000017521