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  4. Recombinant Rat Anion exchange protein 2 (Slc4a2), partial

Recombinant Rat Anion exchange protein 2 (Slc4a2), partial

  • 中文名称：
    大鼠Slc4a2重组蛋白
  • 货号：
    CSB-YP021667RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Slc4a2重组蛋白
  • 货号：
    CSB-EP021667RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Slc4a2重组蛋白
  • 货号：
    CSB-EP021667RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Slc4a2重组蛋白
  • 货号：
    CSB-BP021667RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Slc4a2重组蛋白
  • 货号：
    CSB-MP021667RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc4a2
  • Uniprot No.：
  • 别名：
    Slc4a2; Ae2; B3rp2Anion exchange protein 2; AE 2; Anion exchanger 2; Band 3-related protein 2; B3RP-2; Non-erythroid band 3-like protein; Solute carrier family 4 member 2
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plasma membrane anion exchange protein of wide distribution.
  • 基因功能参考文献：
    1. Results indicate that the increase in bile flow induced by rifampicin is mainly due to increased HCO3 (-) excretion mediated by increased AE2 protein expression and activity. PMID: 26319954
    2. Results suggest that exhaustive running exercise results in elevated band-3 tyrosine phosphorylation and alters band-3 membrane organization. PMID: 24192602
    3. These results demonstrate that NHE1 and AE2 are important regulators of bone growth. PMID: 23059814
    4. the regulation following NH(4)Cl loading of AE2b in the cortical thick ascending limb suggests a role for AE2 in transepithelial bicarbonate reabsorption in this segment PMID: 14749257
    5. Hepatocytic apical targeting of anion exchanger 2 (AE2) isoforms suggests that they all may participate in the canalicular secretion of bicarbonate to bile. PMID: 15184086
    6. regulation of the basolateral Cl(-)/HCO(3)(-) exchanger AE2 plays an important role in the adaptation of bicarbonate absorption in the thick ascending loop of Henle during chronic acid-base disturbances and high sodium intake. PMID: 15579501
    7. Coexpression of carbonic anhydrase IX and SLC4A2 activated SLC4A2 mediated transport. PMID: 17652430

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Anion exchanger (TC 2.A.31) family
  • 数据库链接：

    KEGG: rno:24780

    STRING: 10116.ENSRNOP00000019666

    UniGene: Rn.9860