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  4. Recombinant Rat Cytoplasmic dynein 1 intermediate chain 1 (Dync1i1)

Recombinant Rat Cytoplasmic dynein 1 intermediate chain 1 (Dync1i1)

  • 中文名称：
    大鼠Dync1i1重组蛋白
  • 货号：
    CSB-YP723558RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Dync1i1重组蛋白
  • 货号：
    CSB-EP723558RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Dync1i1重组蛋白
  • 货号：
    CSB-EP723558RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Dync1i1重组蛋白
  • 货号：
    CSB-BP723558RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Dync1i1重组蛋白
  • 货号：
    CSB-MP723558RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dync1i1
  • Uniprot No.：
  • 别名：
    Dync1i1; Dnci1; Dncic1Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; Dynein intermediate chain 1; cytosolic; DH IC-1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-643
  • 氨基酸序列
    MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVPDDS DLDRKRRETE ALLQSIGISP EPPLVQPLHF LTWDTCYFHY LVPTPMSPSS KSVSTPSEAG SQDDLGPLTR TLQWDTDPSV LQLQSDSELG RRLNKLGVSK VTQVDFLPRE VVSYSKETQT PLATHQSEED EEDEEMVEPK VGHDSELENQ DKKQETKEAP PRELTEEEKQ QILHSEEFLI FFDRTIRVIE RALAEDSDIF FDYSGRELEE KDGDVQAGAN LSFNRQFYDE HWSKHRVVTC MDWSLQYPEL MVASYSNNED APHEPDGVAL VWNMKFKKTT PEYVFHCQSS VMSVCFARFH PNLVVGGTYS GQIVLWDNRS HRRTPVQRTP LSAAAHTHPV YCVNVVGTQN AHNLITVSTD GKMCSWSLDM LSTPQESMEL VYNKSKPVAV TGMAFPTGDV NNFVVGSEEG TVYTACRHGS KAGIGEVFEG HQGPVTGINC HMAVGPIDFS HLFVTSSFDW TVKLWTTKHN KPLYSFEDNA DYVYDVMWSP VHPALFACVD GMGRLDLWNL NSDTEVPTAS VAIEGAYALN RVRWAQGGKE VAVGDSEGRI WIYDVGELAV PHNDEWTRFA RTLVEIRANR ADSEEEGAVE LAA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
  • 基因功能参考文献：
    1. the dynein-dynactin interaction proceeds through a disorder-to-order transition PMID: 23577064
    2. the intermediate chain of dynein binds to kinesin light chains 1 and 2. The interaction is both direct and specific PMID: 14985359
  • 亚细胞定位：
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    Dynein intermediate chain family
  • 组织特异性：
    High levels seen in the brain and testis, while a lower level expression is seen in the liver, spleen, kidney, lung, skeletal muscle and heart.
  • 数据库链接：

    KEGG: rno:29564

    STRING: 10116.ENSRNOP00000013184

    UniGene: Rn.11273