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Recombinant Rat Estrogen-related receptor gamma (Esrrg)

  • 中文名称:
    大鼠Esrrg重组蛋白
  • 货号:
    CSB-YP007837RA
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    大鼠Esrrg重组蛋白
  • 货号:
    CSB-EP007837RA
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    大鼠Esrrg重组蛋白
  • 货号:
    CSB-EP007837RA-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    大鼠Esrrg重组蛋白
  • 货号:
    CSB-BP007837RA
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    大鼠Esrrg重组蛋白
  • 货号:
    CSB-MP007837RA
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Esrrg
  • Uniprot No.:
  • 别名:
    Esrrg; Errg; Nr3b3Estrogen-related receptor gamma; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3
  • 种属:
    Rattus norvegicus (Rat)
  • 蛋白长度:
    Full length protein
  • 表达区域:
    1-458
  • 氨基酸序列
    MDSVELCLPE SFSLHYEEEL LCRMSNKDRH IDSSCSSFIK TEPSSPASLT DSVNHHSPGG SSDASGSYSS TMNGHQNGLD SPPLYPSAPI LGGSGPVRKL YDDCSSTIVE DPQTKCEYML NSMPKRLCLV CGDIASGYHY GVASCEACKA FFKRTIQGNI EYSCPATNEC EITKRRRKSC QACRFMKCLK VGMLKEGVRL DRVRGGRQKY KRRIDAENSP YLNPQLVQPA KKPYNKIVSH LLVAEPEKIY AMPDPTVPDS DIKALTTLCD LADRELVVII GWAKHIPGFS TLSLADQMSL LQSAWMEILI LGVVYRSLSF EDELVYADDY IMDEDQSKLA GLLDLNNAIL QLVKKYKSMK LEKEEFVTLK AIALANSDSM HIEDVEAVQK LQDVLHEALQ DYEAGQHMED PRRAGKMLMT LPLLRQTSTK AVQHFYNIKL EGKVPMHKLF LEMLEAKV
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
  • 基因功能参考文献:
    1. ERRgamma was preferentially expressed in brown compared to white fat depots, and ERRgamma was induced during cold-induced browning of subcutaneous white adipose tissue and brown adipogenesis PMID: 23404793
    2. ERRgamma recognizes a tremendously broad range of sequences as a homodimer. PMID: 15475169
    3. Estrogen-related receptor gamma binds to the hepatic pyruvate dehydrogenase kinase (PDK) 4 promoter and stimulates PDK4 expression. PMID: 17079227
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    Nuclear hormone receptor family, NR3 subfamily
  • 数据库链接:

    KEGG: rno:360896

    STRING: 10116.ENSRNOP00000003489

    UniGene: Rn.214491