Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Rat Kelch-like protein 17 (Klhl17)

Recombinant Rat Kelch-like protein 17 (Klhl17)

  • 中文名称：
    大鼠Klhl17重组蛋白
  • 货号：
    CSB-YP818354RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Klhl17重组蛋白
  • 货号：
    CSB-EP818354RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Klhl17重组蛋白
  • 货号：
    CSB-EP818354RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Klhl17重组蛋白
  • 货号：
    CSB-BP818354RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Klhl17重组蛋白
  • 货号：
    CSB-MP818354RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Klhl17
  • Uniprot No.：
  • 别名：
    Klhl17Kelch-like protein 17; Actinfilin
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-640
  • 氨基酸序列
    MQPRGERPAG RTQSPEHSSP GPGPEAPPPP QPPAPEAERA RPRQARPAAP MEGAMQLLSR EGHSVAHNSK RHYHDAFVAM SRMRQRGLLC DIVLHVAAKE IRAHKVVLAS CSPYFHAMFT NEMSESRQTH VTLHDIDPQA LDQLVQFAYT AEIVVGEGNV QTLLPAASLL QLNGVRDACC KFLLSQLDPS NCLGIRGFAD THSCSDLLKA AHRYVLQHFV DVAKTEEFML LPLKQVLELV SSDSLNVPSE EDVYRAVLSW VKHDVDTRRQ HVPRLMKCVR LPLLSRDFLL GHVDAESLVR HHPDCKDLLI EALKFHLLPE QRGVLGTSRT RPRRCEGAGP VLFAVGGGSL FAIHGDCEAY DTRTDRWHVV ASMSTRRARV GVAAVGNRLY AVGGYDGTSD LATVESYDPV TNTWQPEVSM GTRRSCLGVA ALHGLLYAAG GYDGASCLNS AERYDPLTGT WTSIAAMSTR RRYVRVATLD GNLYAVGGYD SSSHLATVEK YEPQVNSWTP VASMLSRRSS AGVAVLEGAL YVAGGNDGTS CLNSVERYST KAGAWESVAP MNIRRSTHDL VAMDGWLYAV GGNDGSSSLN SIEKYNPRTN KWVAASCMFT RRSSVGVAVL ELLNFPPPSS PTLSVSSTSL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes. The BCR(KLHL17) complex mediates the ubiquitination and subsequent degradation of GLUR6. May play a role in the actin-based neuronal function.
  • 基因功能参考文献：
    1. a brain specific Kelch protein, which interacts with F-actin PMID: 12063253
    2. Actinfilin acts as a scaffold, linking kainate-type glutamate receptor subunit GluR6 to the Cul3 ubiquitin ligase to provide a novel mechanism for kainate receptor degradation. PMID: 17062563
  • 亚细胞定位：
    Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 组织特异性：
    Brain specific. Broadly expressed in neurons of most regions of the brain.
  • 数据库链接：

    KEGG: rno:246757

    STRING: 10116.ENSRNOP00000027547

    UniGene: Rn.144676