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  4. Recombinant Rat Translation initiation factor eIF-2B subunit delta (Eif2b4)

Recombinant Rat Translation initiation factor eIF-2B subunit delta (Eif2b4)

  • 中文名称：
    大鼠Eif2b4重组蛋白
  • 货号：
    CSB-YP723561RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Eif2b4重组蛋白
  • 货号：
    CSB-EP723561RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Eif2b4重组蛋白
  • 货号：
    CSB-EP723561RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Eif2b4重组蛋白
  • 货号：
    CSB-BP723561RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Eif2b4重组蛋白
  • 货号：
    CSB-MP723561RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Eif2b4
  • Uniprot No.：
  • 别名：
    Eif2b4; Eif2bd; Translation initiation factor eIF-2B subunit delta; eIF-2B GDP-GTP exchange factor subunit delta
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-524
  • 氨基酸序列
    AAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI GSAVSAAQRQ DPVRELQGTG SQLGGTTGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG EQGGPSPQAC PSTAGEATSG VKRVPEHTQA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLV SGSNARCIAL LHALQQVIQD YTTPPNEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF FNKEVTGMSS SKREEEAKSE LKEAIDRYVQ EKIVLASQAI SRFASKKISD GDVILVYGCS SLVSRILQEA WVEGRRFRVV VVDSRPRLEG RHMLHCLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVTLANWQNN SSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
  • 基因功能参考文献：
    1. insulin-like growth factor 1-induced eIF2B activation in neurons is effected by protein phosphatase 1, the activation of which is mediated by the MEK/MAPK signaling pathway PMID: 12624094
    2. The eukaryotic initiation factor 2B beta, gamma, delta and epsilon subunit protein levels are maximal at embryonic day 18 and then decrease during development. Aged hippocampus contain only trace amounts of these subunits. PMID: 12850562
    3. Significant increases in the relative abundance of the mRNAs coding for the epsilon (33%) and gamma (26%) subunits of eukaryotic initiation factor (eIF) 2B were observed 48 h after the exercise bout. PMID: 14565967
  • 蛋白家族：
    EIF-2B alpha/beta/delta subunits family
  • 数据库链接：

    KEGG: rno:117019

    UniGene: Rn.11060