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  4. Recombinant Saccharomyces cerevisiae Protein BTN2 (BTN2)

Recombinant Saccharomyces cerevisiae Protein BTN2 (BTN2)

  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein BTN2(BTN2),Yeast
  • 货号：
    CSB-YP344873SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein BTN2(BTN2),Yeast
  • 货号：
    CSB-EP344873SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein BTN2(BTN2),Yeast
  • 货号：
    CSB-EP344873SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein BTN2(BTN2),Yeast
  • 货号：
    CSB-BP344873SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein BTN2(BTN2),Yeast
  • 货号：
    CSB-MP344873SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    BTN2
  • Uniprot No.：
  • 别名：
    BTN2; YGR142WProtein BTN2; Batten disease protein 2
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-410
  • 氨基酸序列
    MFSIFNSPCV FEQLPSFSQP LHSRYFDCSS PVSYYPECKR RKAIKANLRA PKKSDANCSE PLRYALAETP NGYTLSLSKR IPYELFSKYV NEKLGELKEN HYRPTYHVVQ DFFGNQYYVE DEADEDALLR SALKDLDFRA IGKKIAKDLF QDYEIELNHR GDELSILSKK DKIFKEFSLD QVFEDVFVIG CGVENIDDGS REKYALLKIG LVKHEEEISE GGINEPKMPI IESKIDESHD DVNMSESLKE EEAEKAKEPL TKEDQIKKWI EEERLMQEES RKSEQEKAAK EDEERQKKEK EARLKARKES LINKQKTKRS QQKKLQNSKS LPISEIEASN KNNNSNSGSA ESDNESINSD SDTTLDFSVS GNTLKKHASP LLEDVEDEEV DRYNESLSRS PKGNSIIEEI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    V-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi. Modulates the rate of arginine uptake. Involved in pH homeostasis. Required for the correct localization of IST2. May be involved in ion homeostasis together with IST2.
  • 基因功能参考文献：
    1. Juxtanuclear deposits of misfolded protein reside in an intranuclear quality control compartment whose formation is dependent on Btn2. PMID: 25672362
    2. Normal levels of the antiprion proteins Btn2 and Cur1 cure most newly formed [URE3] prion variants. PMID: 24938787
    3. Protein redistribution by Btn2 is accompanied by a gradual depletion of Sis1 from the cytosol, which is mediated by the sorting factor Cur1. PMID: 22718905
    4. Btn2-mediated endosomal protein trafficking and prion curing in yeast is regulated by Btn3 PMID: 21441304
    5. Btn2 facilitates specific protein retrieval from a late endosome to the Golgi apparatus, a process which may be adversely affected in patients with Batten disease. PMID: 17101785
    6. Btn2p is part of a system that collects aggregates preventing their efficient distribution to progeny cells PMID: 18833194

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  • 亚细胞定位：
    Cytoplasm. Late endosome.
  • 数据库链接：

    KEGG: sce:YGR142W

    STRING: 4932.YGR142W