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  4. Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C (ahpC)

Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C (ahpC)

  • 中文名称：
    Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C(ahpC),Yeast
  • 货号：
    CSB-YP363197SXB
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C(ahpC),Yeast
  • 货号：
    CSB-EP363197SXB
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C(ahpC),Yeast
  • 货号：
    CSB-EP363197SXB-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C(ahpC),Yeast
  • 货号：
    CSB-BP363197SXB
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Salmonella typhimurium Alkyl hydroperoxide reductase subunit C(ahpC),Yeast
  • 货号：
    CSB-MP363197SXB
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ahpC
  • Uniprot No.：
  • 别名：
    ahpC; STM0608Alkyl hydroperoxide reductase C; EC 1.11.1.15; Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; Thioredoxin peroxidase
  • 种属：
    Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-187
  • 氨基酸序列
    SLINTKIKP FKNQAFKNGE FIEVTEKDTE GRWSVFFFYP ADFTFVCPTE LGDVADHYEE LQKLGVDVYS VSTDTHFTHK AWHSSSETIA KIKYAMIGDP TGALTRNFDN MREDEGLADR ATFVVDPQGI IQAIEVTAEG IGRDASDLLR KIKAAQYVAA HPGEVCPAKW KEGEATLAPS LDLVGKI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  • 基因功能参考文献：
    1. Using bulkier hydroperoxide substrates with higher Km values, ths study found that different efficiencies (kcat/Km) for turnover of AhpC with these substrates are primarily caused by their slower rates of binding. PMID: 25633283
    2. The connection is clarified between peroxiredoxin (Prx) AhpC decamer formation and active site loop dynamics and the impact of their disruption on both catalytic activity and susceptibility of Prxs to inactivation during turnover PMID: 16060667
    3. findings support the modular architecture of AhpF and its need for domain rotations for function, and emphasize the importance of Cys165 in the reductive reactivation of AhpC. PMID: 17441733
    4. Salmonella typhimurium alkyl hydroperoxide reductase C component substrate specificity profile and redox potential were studied. PMID: 18165315
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Peroxiredoxin family, AhpC/Prx1 subfamily
  • 数据库链接：

    KEGG: stm:STM0608

    STRING: 99287.STM0608