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  4. Recombinant Schizosaccharomyces pombe RNA polymerase II transcription factor B subunit 2 (tfb2)

Recombinant Schizosaccharomyces pombe RNA polymerase II transcription factor B subunit 2 (tfb2)

  • 中文名称：
    庞贝裂殖酵母tfb2重组蛋白
  • 货号：
    CSB-YP311243SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母tfb2重组蛋白
  • 货号：
    CSB-EP311243SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母tfb2重组蛋白
  • 货号：
    CSB-EP311243SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母tfb2重组蛋白
  • 货号：
    CSB-BP311243SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母tfb2重组蛋白
  • 货号：
    CSB-MP311243SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    tfb2
  • Uniprot No.：
  • 别名：
    tfb2; SPBC13G1.13; SPBC31F10.01; General transcription and DNA repair factor IIH subunit tfb2; TFIIH subunit tfb2; RNA polymerase II transcription factor B subunit 2
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-447
  • 氨基酸序列
    MQAEFKSSIN DFLEQLPNHA RLYQKPAACL AVFRLLPILA RQYVMSMLFN PMPVALSDFD LWIKLSSKVY QSESFNKLVR MHIFQFDGQY ITLNSEFRKQ FITALTGGGN HNSFGVPCTD EDKHLVTVDF LDAYAKETWE TILHFMVGTP EAKFPGEGVL SLLKRGGLMS GPKNQLRITR AGFQFLLQDI NAQIWTLLLD YLKLSEDTHM DPVQVLHFLF MLGSLDLGRA YSVDFLTDTQ QIMLEDLREY GLVYQRKITS KRFYPTRLAT GLTTDYRSLH GKQSENDDDK GFIIVETNYR LYAYTSSPLQ IAIIGLFANL RARFSNLVVG VITRDSIRRA LMNGIAAEQI ITYLTTHAHP QMRSNVPLLP PTLVDQIYLW ELEKNRLRAT PGILFRDFLT DSGFDQAVEY AKELGVLVWD SSLKRMFFIT TTGAQPMIAY LKRRAVK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TFB2 family
  • 数据库链接：

    KEGG: spo:SPBC13G1.13

    STRING: 4896.SPBC13G1.13.1