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  4. Recombinant Schizosaccharomyces pombe Transcription factor ste11 (ste11)

Recombinant Schizosaccharomyces pombe Transcription factor ste11 (ste11)

  • 中文名称：
    庞贝裂殖酵母ste11重组蛋白
  • 货号：
    CSB-YP334159SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母ste11重组蛋白
  • 货号：
    CSB-EP334159SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母ste11重组蛋白
  • 货号：
    CSB-EP334159SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母ste11重组蛋白
  • 货号：
    CSB-BP334159SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母ste11重组蛋白
  • 货号：
    CSB-MP334159SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ste11
  • Uniprot No.：
  • 别名：
    ste11; stex; SPBC32C12.02; Transcription factor ste11
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-468
  • 氨基酸序列
    MSASLTAEQK DQKSSVKRPL NSFMLYRRDR QAEIPTSNHQ SISRIIGQLW RNESAQVKKY YSDLSALERQ KHMLENPEYK YTPKKRSTVR RRHKKVSPSS GSFVASDYVV LQQIAQSSKT LKQTEPEKPV NEEETLAALL APALSYPKSG KSNLIETSEL SCLSSSPMIR SHTIPSLSFT DQVSTTISTL DKSEQAPSSL GIYYRSPSSG SPIGRTKSVC LANKARIVPK RSMSSDGCVD KSYQMSKTPS LEANLPQNSS NCSARRVPKF DSKGTVSEQS NSDSPELSAD KVLSHCSPID ARPSTPSCPN ASISPKTPNT GDHYGFDGAE YLGTPLSVGS TTAYLYGQET ELLSTPYCHT SYPAMSRLNS SSGYTCVSSS SVTNSGHTEN NTWRSDEQSK GFVDINSFSQ SLFSNGNYEF AAHSQELDDL FSQITDFTST DPIASSLKDA NSLGPSLLEP WLPNSNLF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Key transcription factor for sexual development. Activates the transcription of the matp, matm, mei2, mfm, ste6 and rgs1 genes. Binds specifically to a DNA fragment carrying a 10-base motif 5'-TTCTTTGTTY-3'.
  • 基因功能参考文献：
    1. REVIEW: Regulation of entry into gametogenesis by Ste11 PMID: 24256273
    2. Msa2 may regulate the translation of Ste11, be a component of stress granules that form in response to glucose starvation, and regulate the sexual differentiation of S. pombe. PMID: 21409593
    3. Study conclude that both the PKA and the TOR pathways inhibit Ste11 nuclear accumulation to repress Ste11-dependent gene expression. PMID: 20634885
    4. Ste11 transcription factor becomes constitutively expressed in cells with induced mitogen-activated protein kinase kinase kinase (MAP3K) Byr2. PMID: 15713656
    5. In fission yeast, induction of the transcription factor Ste11 triggers sexual differentiation. PMID: 17289922
    6. Data show that the SAGA subunit Spt8 is required for the induction of ste11(+) upon nutrient starvation. and SAGA is physically associated with the ste11(+) promoter independent of nutrient levels. PMID: 19056896

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  • 亚细胞定位：
    Nucleus. Cytoplasm. Note=Accumulates in the nucleus under conditions of nitrogen starvation and in the presence of mating pheromones.
  • 数据库链接：

    KEGG: spo:SPBC32C12.02

    STRING: 4896.SPBC32C12.02.1