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  4. Recombinant Xenopus laevis Serine/threonine-protein kinase NLK2 (nlk.2)

Recombinant Xenopus laevis Serine/threonine-protein kinase NLK2 (nlk.2)

  • 中文名称：
    有爪蟾蜍nlk.2重组蛋白
  • 货号：
    CSB-YP819135XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍nlk.2重组蛋白
  • 货号：
    CSB-EP819135XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍nlk.2重组蛋白
  • 货号：
    CSB-EP819135XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍nlk.2重组蛋白
  • 货号：
    CSB-BP819135XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍nlk.2重组蛋白
  • 货号：
    CSB-MP819135XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    nlk.2
  • Uniprot No.：
  • 别名：
    nlk.2; nlk; Serine/threonine-protein kinase NLK2; EC 2.7.11.24; Nemo-like kinase 2; Nlk.2; xNLK
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-447
  • 氨基酸序列
    MAFPGSGRSI PGQLCAGVFS GLIQPPLGQK FYCPNGGGAV PSPLPQALSA PQCNGEGRDP EPDRPIGYGA FGVVWSVTDP RDGKRVALKK MPNVFQNLVS CKRVFRELKM LCFFKHDNVL SALDILQPPQ IDCFEEIYVI TELMQTDLHK VIVSPQPLSS DHIKVFLYQI LRGLKYLHSA GILHRDIKPG NLLVNSNCVL KICDFGLARV EELDESQHMT QEVVTQYYRA PEILMGSRHY RSAIDIWSVG CIFAELLGRR ILFQAQSPIQ QLDLITDLLG TPPLTAMRSA CEGARAHILR GPHKPPSLSV LYMLSGEATH EAVHLLCRML LFDPLKRISA KDALAHPYLE EGRLRYHTCM CHCCYSVSSG RVYTADFEPT ATNRFDDSYE KSLTSVWQVK ELVHRFITDQ HQGKRPPLCI NPHSAAFKTF IRSTAWHSSK VSKKEER
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Negatively regulates Wnt/beta-catenin-signaling during development. Plays a role together with sox11 in neural induction during early embryogenesis. Involved in TGFbeta-mediated mesoderm induction in early embryos, acting downstream of map3k7/tak1 to phosphorylate stat3.1. Augments the rnf138/narf-directed ubiquitination and degradation of tcf/lef by enhancing the association of rnf138/narf and tcf/lef. Phosphorylates mef2a to play a role in anterior neural development, including eye formation.
  • 基因功能参考文献：
    1. These results provide the first evidence that p38 specifically regulates NLK function, which is required for anterior formation in Xenopus development. PMID: 19933839
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
  • 组织特异性：
    Expressed widely in the ectoderm during early gastrula stage when neural induction is taking place. Expressed in the head region of neurula stage embryos. At the end of neurulation, expression becomes localized to the nervous system, and is restricted to
  • 数据库链接：

    KEGG: xla:398295

    UniGene: Xl.7148