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  4. Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-1 (irx1)

Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-1 (irx1)

  • 中文名称：
    热带爪蟾irx1重组蛋白
  • 货号：
    CSB-YP739633XBF
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    热带爪蟾irx1重组蛋白
  • 货号：
    CSB-EP739633XBF
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    热带爪蟾irx1重组蛋白
  • 货号：
    CSB-EP739633XBF-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    热带爪蟾irx1重组蛋白
  • 货号：
    CSB-BP739633XBF
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    热带爪蟾irx1重组蛋白
  • 货号：
    CSB-MP739633XBF
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    irx1
  • Uniprot No.：
  • 别名：
    irx1; iro1Iroquois-class homeodomain protein irx-1; Iroquois homeobox protein 1
  • 种属：
    Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-467
  • 氨基酸序列
    MSFPQLGYPQ YLSAGQAAVY GGERPGVLAA AAAAAAAAAA AGSGRPTGAD LGSSSTAAVT SVLGMYASPY SAPNYSAFLP YTTDLTLFSQ MGSQYELKDN PGVHPATFAA HTTPGYYPYG QFQYGDPGRP KNATRESTST LKAWLNEHRK NPYPTKGEKI MLAIITKMTL TQVSTWFANA RRRLKKENKV TWGARSKEDD NIFGSDTEGD HEKNEDDEEI DLESIDIDKI DDNDGEQSNE EEDEKLEHLR QGEKESFKKE SEVMIPSSDG LKSKDSLSLG KESSDTSNTR IVSPGGQGNI QVPPHNKPKI WSLAETATSP DGALKSSPPP SQANHTSPPI QHPAFLPSHG LYTCQIGKFH NWTNGAFLTQ SSLINMRSLL GVNPHHVAHH NHHHLQAHQQ APLLATNLSS LSSDKTPERT SPKHSDRENL PRTESPPQLK PSFQAVRENT LSQQEGTSRI LTALPSA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds to the bmp4 promoter to repress gene expression and thus mediate down-regulation of bmp4 by wnt signaling. Controls multiple processes through bmp4-repression including neural plate development, neural crest specification and Spemann organizer development. Involved in the specification of the preplacodal field at the anterior border of the neural plate. Regulates the genetic cascade of interactions that are necessary for positioning the isthmus organizer and the formation of the midbrain-hindbrain boundary. Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling. Subsequently required for proper formation of the intermediate tubule segment of the pronephros. Acts principally as a transcriptional activator during pronephros development.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TALE/IRO homeobox family
  • 组织特异性：
    Expressed in the neural plate in overlapping patterns with other irx members, which all share an anterior border of expression. Also expressed in the mesoderm, placodes and notochord. Broadly expressed in the tailbud rhombencephalon (hindbrain). Outside t
  • 数据库链接：

    KEGG: xtr:100038208

    STRING: 8364.ENSXETP00000061991

    UniGene: Str.31298