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  4. Recombinant Bovine Transmembrane protein 108 (TMEM108)

Recombinant Bovine Transmembrane protein 108 (TMEM108)

  • 中文名称：
    牛TMEM108重组蛋白
  • 货号：
    CSB-CF023677BO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    TMEM108
  • Uniprot No.：
  • 别名：
    TMEM108; Transmembrane protein 108; Retrolinkin
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    29-583
  • 氨基酸序列
    AQEPSPRESLQVSPSGTIPGTMVTASLSSTRHSSMVATPASVVTPTPHPDGPSSQATAPMATTTPHLDGHPPTNTISTIMATASTPHSEGSLSTGPLPAAMATTSSHSEGRAPGETAPTILLTKPGEATSRPPTAPSRATIRRPPRPPGSSRKGAGSSPRPIPAAPSGHAGRKDGQRGRNQSSTHLGQKRPLGKIFQIYKGNFTGSVEPDPSTFTPRNPLWGYSSSPQPQTVAATSAPSRTSWVPPTTPLVPVEDKPSLSRADQGGGSTFTSQGGEPDATAASGTPASQQRAPVPSQRPHGDPQDGSSHSDSWLTVTPGTSRPPSTNSGVFAATTGPIQAAFDASVSVPSEGLPQGTSLAPQAPAHPTWASESTVSQAEEKAVATPTPTMMGRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQQRATICLSKMDIAWVILAISVPISSCSVLLTVCCLRRKKKPANPENSLSYWNNAITMDYFSKHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density. Endosome membrane. Cell projection, axon. Cell projection, dendrite. Early endosome.
  • 数据库链接：

    KEGG: bta:511034

    STRING: 9913.ENSBTAP00000024636

    UniGene: Bt.17020