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  4. Recombinant Drosophila melanogaster Putative odorant receptor 67d (Or67d)

Recombinant Drosophila melanogaster Putative odorant receptor 67d (Or67d)

  • 中文名称：
    黑腹果蝇Or67d重组蛋白
  • 货号：
    CSB-CF893325DLU
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Or67d
  • Uniprot No.：
  • 别名：
    Or67d; CG14157; Odorant receptor 67d
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-391
  • 氨基酸序列
    MLKMAKVEPVERYCKVIRMIRFCVGFCGNDVADPNFRMWWLTYAVMAAIAFFFACTGYTI YVGVVINGDLTIILQALAMVGSAVQGLTKLLVTANNASHMREVQNTYEDIYREYGSKGDE YAKCLEKRIRITWTLLIGFMLVYIILLGLVITFPIFYLLILHQKVLVMQFLIPFLDHTTD GGHLILTAAHVILITFGGFGNYGGDMYLFLFVTHVPLIKDIFCVKLTEFNELVMKRNDFP KVRAMLCDLLVWHQLYTRMLQTTKKIYSIVLFVQLSTTCVGLLCTISCIFMKAWPAAPLY LLYAAITLYTFCGLGTLVENSNEDFLSVIYTNCLWYELPVKEEKLIIMMLAKAQNEVVLT AADMAPLSMNTALQLTKGIYSFSMMLMNYLG
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in detection and sensitivity to pheromones and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA). Acts in concert with Snmp and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Necessary to mediate behavioral responses to cVA by regulating both male and female mating behavior. Activation of Or67d neurons by cVA inhibits courtship of other males, whereas in females their activation promotes receptivity to other males. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
  • 基因功能参考文献：
    1. desensitization of Or67d is sensitive to neurotransmitter antagonists, which suggests that the site of action of habituation is within the neural network in the antennal lobe PMID: 26252206
    2. the Drosophila melanogaster male-specific pheromone 11-cis-vaccenyl acetate (cVA) acts through the receptor Or67d to regulate both male and female mating behaviour PMID: 17392786
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Insect chemoreceptor superfamily, Heteromeric odorant receptor channel (TC 1.A.69) family, Or67d subfamily
  • 组织特异性：
    Expressed in antenna.
  • 数据库链接：

    KEGG: dme:Dmel_CG14157

    STRING: 7227.FBpp0076026

    UniGene: Dm.27107