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  4. Recombinant Human Solute carrier family 25 member 47 (SLC25A47)

Recombinant Human Solute carrier family 25 member 47 (SLC25A47)

  • 中文名称：
    人SLC25A47重组蛋白
  • 货号：
    CSB-CF750897HU
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    SLC25A47
  • Uniprot No.：
  • 别名：
    SLC25A47; C14orf68; HDMCP; HMFN1655; Solute carrier family 25 member 47; Hepatocellular carcinoma down-regulated mitochondrial carrier protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-308
  • 氨基酸序列
    MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPV CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYK GSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDV IKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVL RLARGLLT
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Uncoupling protein which may catalyze the physiological 'proton leak' in liver. Overexpression induces the dissipation of mitochondrial membrane potential.
  • 基因功能参考文献：
    1. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20877624
    3. hepatocellular carcinoma down-regulated mitochondrial carrier protein is a novel liver-specific uncoupling protein PMID: 15322095
    4. HDMCP might function through promoting ATP depletion and decreasing H(2)O(2) production. PMID: 19303656
  • 亚细胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 组织特异性：
    Specifically expressed in liver.
  • 数据库链接：

    HGNC: 20115

    OMIM: 609911

    KEGG: hsa:283600

    STRING: 9606.ENSP00000354886

    UniGene: Hs.108268