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  4. Recombinant Mouse Solute carrier family 25 member 46 (Slc25a46)

Recombinant Mouse Solute carrier family 25 member 46 (Slc25a46)

  • 中文名称：
    小鼠Slc25a46重组蛋白
  • 货号：
    CSB-CF875118MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Slc25a46
  • Uniprot No.：
  • 别名：
    Slc25a46; Solute carrier family 25 member 46
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-418
  • 氨基酸序列
    MHPRRPEGFDGLGYRGGVRDDPAFGGPFHARSFGSGTELGHWVTTPPDIPGSRNLHWGEK SPSYGVPSAPPTLEGSAEEPFPGGGEGPRPGPSSEQLNRFAGFGIGLASLFTENVLAHPC IVLRRQCQVNYHARHYHLTPFSIINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII SEFTPLPREVSHKLNPKQIGEHLLLKCLTYMVAMPFYSASLIETVQSEIIRDNTGILECV KEGIGRVIGLGVPHSKRLLPLFSLIFPTVLHGVLHYIISSIIQKIVLLILKRKTYNSHLA ESTSPMQNMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL PINTQYEGMRDCINTIKQEEGVFGFYKGFGAVIIQYTLHATILQITKMIYSTLLQNSI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
  • 基因功能参考文献：
    1. we showed that the Slc25a46 disruption caused a fusion/fission imbalance and an abnormal mitochondrial architecture that disturbed mitochondrial metabolism. These data extended the range of phenotypes associated with Slc25a46 dysfunction. Moreover, this Slc25a46 knock-out mouse model should be useful to further elucidate the role of SLC25A46 in mitochondrial dynamics PMID: 28376083
    2. Our mutant mice provide a valid model for understanding the mechanistic basis of the complex SLC25A46-mediated pathologies, as well as for screening potential therapeutic interventions. PMID: 28376086
  • 亚细胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Mitochondrial carrier (TC 2.A.29) family
  • 数据库链接：

    KEGG: mmu:67453

    STRING: 10090.ENSMUSP00000053325

    UniGene: Mm.23896