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  4. Recombinant Neurospora crassa Mitochondrial intermembrane space import and assembly protein 40 (mia-40)

Recombinant Neurospora crassa Mitochondrial intermembrane space import and assembly protein 40 (mia-40)

  • 中文名称：
    小神经孢子虫mia-40重组蛋白
  • 货号：
    CSB-CF745780NHA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    mia-40
  • Uniprot No.：
  • 别名：
    mia-40; tim-40; NCU04945; Mitochondrial intermembrane space import and assembly protein 40; Mitochondrial import inner membrane translocase TIM40
  • 种属：
    Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    34-298
  • 氨基酸序列
    ASTTSAPKKKSTWKGAAVRWGLAVAAVYYYNTSPIFSDELPETAGTAPSQLTDADLPTVD AIVEEKRRQAAEHAAARKAAQAAAKAAATPATPSESVEEQITKAEAEAEAVPEGDSKPRS ESTEGVIPEAGASPEALQEEADAQGAFNPETGEINWDCPCLGGMAHGPCGEEFKAAFSCF VYSTEEPKGMDCIEKFSHMQDCFRKYPEVYGAELADDEEAERASAAAPAAEGTPAKEEPV ENKKEEALEPATHDATAANNNKKQQ
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.
  • 亚细胞定位：
    Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
  • 数据库链接：

    KEGG: ncr:NCU04945