CHMP4C
Charged multivesicular body protein 4c is a protein in humans that is encoded by CHMP4C gene. Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage
CHMP4C Antibodies
CHMP4C for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
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CSB-PA853396LA01HU | CHMP4C Antibody | Human | ELISA, IHC |
CSB-PA853396LB01HU | CHMP4C Antibody, HRP conjugated | Human | ELISA |
CSB-PA853396LD01HU | CHMP4C Antibody, Biotin conjugated | Human | ELISA |
CHMP4C Proteins
CHMP4C Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
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CSB-YP710064RA CSB-EP710064RA CSB-BP710064RA CSB-MP710064RA CSB-EP710064RA-B |
Recombinant Rat Charged multivesicular body protein 4c (Chmp4c) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4C Proteins for Xenopus laevis (African clawed frog)
产品货号 | 产品名称 | 来源 |
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CSB-YP743439XBE CSB-EP743439XBE CSB-BP743439XBE CSB-MP743439XBE CSB-EP743439XBE-B |
Recombinant Xenopus laevis Charged multivesicular body protein 4c (chmp4c) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4C Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
产品货号 | 产品名称 | 来源 |
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CSB-YP760815DIL CSB-EP760815DIL CSB-BP760815DIL CSB-MP760815DIL CSB-EP760815DIL-B |
Recombinant Danio rerio Charged multivesicular body protein 4c (chmp4c) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4C Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP853396HU CSB-EP853396HU CSB-BP853396HU CSB-MP853396HU CSB-EP853396HU-B |
Recombinant Human Charged multivesicular body protein 4c (CHMP4C) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHMP4C Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP880514MO CSB-EP880514MO CSB-BP880514MO CSB-MP880514MO CSB-EP880514MO-B |
Recombinant Mouse Charged multivesicular body protein 4c (Chmp4c) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |