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CYP11A1

CYP11A1,即细胞色素P450家族11亚家族A1,别名P450scc、CYPXIA1、CYPXI等。它是一种由CYP11A1基因编码的酶,属于细胞色素P450超家族成员,在肾上腺皮质细胞中表达。CYP11A1的作用机制涉及催化胆固醇侧链的裂解,是合成类固醇激素的第一步,将胆固醇转化为孕烯醇酮。CYP11A1参与了肾上腺皮质激素的生物合成过程,包括皮质醇、醛固酮和性激素等。CYP11A1的活性对于维持正常的生理功能和应对压力至关重要。此外,CYP11A1的功能异常与某些疾病有关,如肾上腺增生、肾上腺皮质癌等。

热销产品

Recombinant Human Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1),Biotinylated (CSB-EP006389HU-B)

验证数据

CSB-EP006389HU-B

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CYP11A1 Antibody (CSB-PA006389LA01HU)

验证数据

CSB-PA006389LA01HU

Western blot
All lanes: CYP11A1 antibody at 2µg/ml + Rat adrenal gland tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61, 43 kDa
Observed band size: 61 kDa

CSB-PA006389LA01HU

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA006389LA01HU at dilution of 1:100

CYP11A1 Antibodies

CYP11A1 for Homo sapiens (Human)

CYP11A1 Proteins

CYP11A1 Proteins for Homo sapiens (Human)