Ccr6
CCR6在细胞的信号传导中扮演重要角色，作为G蛋白偶联受体的成员。它包含了七个跨膜区域，两个胞浆区域和一个胞外区域。这种结构使得CCR6能够与其配体结合并传递信号其配体包括CCL20（也称为MIP-3α），它能够引导特定类型的免疫细胞向特定组织或器官迁移。除了免疫细胞的迁移外，CCR6也在其他生理和病理过程中发挥作用，例如炎症、肿瘤转移和神经发育。CCR6通过激活多种信号通路来介导其生物学效应。主要的信号通路包括G蛋白偶联受体信号通路（通过激活G蛋白）和非G蛋白偶联受体信号通路（通过激活丝裂原激活蛋白激酶（MAPK）信号通路等）。这些信号通路的激活可以导致细胞迁移、增殖、分化和其他生物学响应。
热销产品
Recombinant Human C-C chemokine receptor type 6(CCR6)-VLPs (Active)
验证数据
CSB-MP004845HU is detected by Mouse anti-6*His monoclonal antibody. The two bands respectively correspond to monomer, Homodimer.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCR6 at 10μg/mL can bind Anti-CCR6 recombinant antibody (CSB-RA004845MA1HU)， the EC50 is 44.79-56.10 ng/mL.VLPs (CSB-MP3838) is negative control.
Ccr6 Antibodies
Ccr6 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004845EA01HU | CCR6 Antibody | Human | ELISA, WB |
| CSB-PA004845EC01HU | CCR6 Antibody, FITC conjugated | Human | |
| CSB-PA943255 | CCR6 Antibody | Human | ELISA,WB,IHC |
| CSB-PA244343 | CCR6 Antibody | Human | ELISA,IHC |
| CSB-RA004845MA1HU | CCR6 Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-RA004845MA2HU | CCR6 Recombinant Monoclonal Antibody | Human | Non-conjugated |
Ccr6 Proteins
Ccr6 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004845HU1 CSB-BP004845HU1 CSB-MP004845HU1 CSB-EP004845HU1-B |
Recombinant Human C-C chemokine receptor type 6 (CCR6), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004845HU | Recombinant Human C-C chemokine receptor type 6 (CCR6) | in vitro E.coli expression system |
| CSB-CF004845HUa2 | Recombinant Human C-C chemokine receptor type 6 (CCR6) | in vitro E.coli expression system |
| CSB-EP004845HU1 | Recombinant Human C-C chemokine receptor type 6 (CCR6), partial | E.coli |
| CSB-MP004845HU | Recombinant Human C-C chemokine receptor type 6(CCR6)-VLPs (Active) | Mammalian cell |
Ccr6 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004845MO1 CSB-EP004845MO1 CSB-BP004845MO1 CSB-MP004845MO1 CSB-EP004845MO1-B |
Recombinant Mouse C-C chemokine receptor type 6 (Ccr6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004845MO | Recombinant Mouse C-C chemokine receptor type 6 (Ccr6) | in vitro E.coli expression system |
