Cd44
CD44是一种细胞表面I型跨膜糖蛋白，属于黏附分子家族。CD44包括标准亚型（CD44s）和CD44变异亚型（CD44v）。CD44作为一种广谱表达的细胞粘附分子，参与细胞增殖、分化、迁移，血管生成等生物学过程，对于介导细胞信号转导，调节组织稳态等功能具有关键作用。CD44也被认为是一种整合跨膜糖蛋白，能够接受细胞微环境的细胞因子的作用，将接收的信号进行整合，通过裂解酶的作用释放CD44胞内域，将其信号传到细胞核。CD44也是公认的肿瘤干细胞的标志物，是上皮细胞间充质转化（EMT）关键调节因子，参与肿瘤的发生，进展和转移。近年来，越来越多的研究发现CD44与多种肿瘤的发生、生长、侵袭、转移和预后密切相关。
Recombinant Human CD44 活性蛋白实验验证数据
SDS-PAGE
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Measured by its binding ability in a functional ELISA. Immobilized CD44 at 2 μg/ml can bind Anti-CD44 mouse monoclonal antibody(CSB-MA004938A0m, antigen from E.coli), the EC50 of the CD44 protein is 11.89-14.94 ng/ml.
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Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of CSB-MP004938HU(F1) could indicate that this peptide derived from Mammalian Cell-expressed Homo sapiens (Human) CD44.
Cd44 Antibodies
Cd44 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004938GA01HU | CD44 Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA644696 | CD44 Antibody | Human,Rat | ELISA,WB,IF |
| CSB-PA135522 | Phospho-CD44 (Ser706) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA001460 | CD44 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA080035 | Phospho-CD44 (S706) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA282285 | CD44 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA685145 | CD44 Antibody | Human | ELISA,WB |
| CSB-PA191560 | CD44 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA004938A0HU | CD44 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC |
| CSB-MA004938A0m | CD44 Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
| CSB-MA247417 | CD44 Monoclonal Antibody | Human | ELISA, IHC |
Cd44 Proteins
Cd44 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004938MO1 CSB-EP004938MO1 CSB-BP004938MO1 CSB-MP004938MO1 CSB-EP004938MO1-B |
Recombinant Mouse CD44 antigen (Cd44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004938MO | Recombinant Mouse CD44 antigen (Cd44) | in vitro E.coli expression system |
Cd44 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004938HU(F1) CSB-BP004938HU(F1) CSB-EP004938HU(F1)-B |
Recombinant Human CD44 antigen (CD44), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP004938HU | Recombinant Human CD44 antigen (CD44), partial | E.coli |
| CSB-CF004938HU | Recombinant Human CD44 antigen (CD44), partial | in vitro E.coli expression system |
| CSB-EP004938HU(F1) | Recombinant Human CD44 antigen (CD44), partial | E.coli |
| CSB-EP004938HU1(F1) | Recombinant Human CD44 antigen (CD44), partial | E.coli |
| CSB-MP004938HU(F1) | Recombinant Human CD44 antigen (CD44), partial (Active) | Mammalian cell |
| CSB-MP004938HU(F1)j1-B | Recombinant Human CD44 antigen (CD44), partial,Biotinylated (Active) | Mammalian cell |
Cd44 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004938RA1 CSB-EP004938RA1 CSB-BP004938RA1 CSB-MP004938RA1 CSB-EP004938RA1-B |
Recombinant Rat CD44 antigen (Cd44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004938RA | Recombinant Rat CD44 antigen (Cd44) | in vitro E.coli expression system |
Cd44 Proteins for Papio hamadryas (Hamadryas baboon)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004938ERJ1 CSB-EP004938ERJ1 CSB-BP004938ERJ1 CSB-MP004938ERJ1 CSB-EP004938ERJ1-B |
Recombinant Papio hamadryas CD44 antigen (CD44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004938ERJ | Recombinant Papio hamadryas CD44 antigen (CD44) | in vitro E.coli expression system |
Cd44 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004938DXU1 CSB-EP004938DXU1 CSB-BP004938DXU1 CSB-MP004938DXU1 CSB-EP004938DXU1-B |
Recombinant Cricetulus griseus CD44 antigen (CD44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004938DXU | Recombinant Cricetulus griseus CD44 antigen (CD44) | in vitro E.coli expression system |
Cd44 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP635685DO CSB-EP635685DO CSB-BP635685DO CSB-MP635685DO CSB-EP635685DO-B |
Recombinant Dog CD44 antigen (CD44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cd44 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP643679BO CSB-EP643679BO CSB-BP643679BO CSB-MP643679BO CSB-EP643679BO-B |
Recombinant Bovine CD44 antigen (CD44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cd44 Proteins for Mesocricetus auratus (Golden hamster)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP723318MRG CSB-EP723318MRG CSB-BP723318MRG CSB-MP723318MRG CSB-EP723318MRG-B |
Recombinant Mesocricetus auratus CD44 antigen (CD44), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cd44 ELISA Kit
Cd44 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E11846h | Human cluster Of differentiation,CD44 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 19.5 pg/mL |
