Cdh5

CDH5，即血管内皮钙粘蛋白，别名VE-cadherin/Cadherin-5。它是一种由CDH5基因编码的II型经典钙粘蛋白家族成员，主要在血管内皮细胞中表达。CDH5的作用机制涉及介导内皮细胞间的同质性粘附，通过其细胞外结构域与相邻细胞的CDH5分子相互作用，形成稳定的粘附连接。这种粘附对于维持血管完整性和调节血管通透性至关重要。此外，CDH5与α-连环蛋白结合，形成与细胞骨架的连接，参与调控内皮细胞的极性和血管腔的形成。CDH5的功能还涉及到与KRIT1和PAR-1等蛋白的相互作用，共同维持内皮细胞的稳定性和功能。CDH5在生物学上的意义主要体现在其对血管内皮细胞生物学的调控作用。它参与了多种生理过程，包括血管新生、血管稳定和炎症反应。在肿瘤发生发展过程中，CDH5的表达水平和功能异常与肿瘤血管生成、肿瘤细胞的侵袭和转移密切相关。此外，CDH5还参与了内皮细胞的屏障功能和细胞信号传导，影响细胞增殖、迁移和分化。因此，CDH5是血管相关疾病研究和治疗中的一个重要靶点，例如在抗血管生成治疗和肿瘤治疗中具有潜在的应用价值。

热销产品

CDH5 Antibody (CSB-PA07519A0Rb)

验证数据

Western Blot
Positive WB detected in: Mouse lung tissue, Mouse kidney tissue
All lanes: CDH5 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 88, 75 kDa
Observed band size: 88 kDa

Immunofluorescent analysis of HepG2 cells using CSB-PA07519A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Mouse Cadherin-5(CDH5) ELISA kit (CSB-EL005054MO)

验证数据

货号：CSB-EL005054MO

规格：96T/48T

灵敏度：0.058 ng/mL

检测范围：0.235 ng/mL-15 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Cdh5 Antibody

Cdh5 Protein

Cdh5 ELISA Kit

Cdh5 Antibodies

Cdh5 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA868788	Phospho-CDH5 (Tyr731) Antibody	Human,Mouse	ELISA,WB
CSB-PA006270	CDH5 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA006366	Phospho-CDH5 (Y731) Antibody	Human,Mouse	WB, IHC, ELISA
CSB-PA006367	CDH5 Antibody	Human,Mouse	WB, IHC, ELISA
CSB-PA947781	CDH5 Antibody	Human	ELISA,IHC
CSB-PA102499	CDH5 Antibody	Human	ELISA,IHC
CSB-PA440133	CDH5 Antibody	Human	ELISA,IHC
CSB-PA07519A0Rb	CDH5 Antibody	Human, Mouse	ELISA, WB, IF
CSB-PA07519C0Rb	CDH5 Antibody, FITC conjugated	Human
CSB-PA07519D0Rb	CDH5 Antibody, Biotin conjugated	Human	ELISA
CSB-MA249655	CDH5 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-MA554141	CDH5 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC

Cdh5 Proteins

Cdh5 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP005054HU1 CSB-EP005054HU1 CSB-BP005054HU1 CSB-MP005054HU1 CSB-EP005054HU1-B	Recombinant Human Cadherin-5 (CDH5), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF005054HU	Recombinant Human Cadherin-5 (CDH5)	in vitro E.coli expression system

Cdh5 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP005054MO1 CSB-EP005054MO1 CSB-BP005054MO1 CSB-MP005054MO1 CSB-EP005054MO1-B	Recombinant Mouse Cadherin-5 (Cdh5), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF005054MO	Recombinant Mouse Cadherin-5 (Cdh5)	in vitro E.coli expression system

Cdh5 Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP005054PI1 CSB-EP005054PI1 CSB-BP005054PI1 CSB-MP005054PI1 CSB-EP005054PI1-B	Recombinant Pig Cadherin-5 (CDH5), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF005054PI	Recombinant Pig Cadherin-5 (CDH5)	in vitro E.coli expression system

Cdh5 Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP764929BO CSB-EP764929BO CSB-BP764929BO CSB-MP764929BO CSB-EP764929BO-B	Recombinant Bovine Cadherin-5 (CDH5), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli