DKK1

DKK1是一种分泌性蛋白质，通常以分泌形式存在于细胞外。它包含一个信号肽（用于分泌）和一个成熟的蛋白质部分。DKK1被认为是Wnt信号通路的抑制剂，这是一种重要的细胞信号传导通路，参与细胞增殖、分化和胚胎发育等过程。此外，DKK1在骨代谢中也扮演着重要角色。它具有抑制骨细胞活性的作用，导致骨吸收和骨形成之间的平衡失调。由于DKK1在多个生理和病理过程中的关键作用，研究人员正在探索将其作为潜在治疗靶点的可能性。特别是在骨相关疾病和一些肿瘤的治疗中，通过调节DKK1的功能，可能提供新的治疗策略。

热销产品

● Recombinant Human Dickkopf-related protein 1(DKK1) (Active) CSB-MP006920HU(A4)

验证数据

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

High Purity Validated of CSB-MP006920HU(A4)

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DKK1 at 2 μg/mL can bind Anti-DKK1 recombinant antibody (CSB-RA006920MA1HU), the EC₅₀ is 1.283-2.544 ng/mL.

DKK1 Antibody

DKK1 Protein

DKK1 ELISA Kit

DKK1 Antibodies

DKK1 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA006126	DKK1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA120268	DKK1 Antibody	Human,Mouse	ELISA,WB
CSB-PA06219A0Rb	DKK1 Antibody	Human	ELISA, IHC, IF
CSB-RA576260A0HU	DKK1 Recombinant Monoclonal Antibody	Human	ELISA, WB

DKK1 Proteins

DKK1 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP006920HU CSB-BP006920HU CSB-MP006920HU CSB-EP006920HU-B	Recombinant Human Dickkopf-related protein 1 (DKK1), partial Yeast	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006920HU	Recombinant Human Dickkopf-related protein 1 (DKK1), partial Escherichia Coli	E.coli
CSB-MP006920HU(A4)	Recombinant Human Dickkopf-related protein 1 (DKK1) (Active)	Mammalian cell

DKK1 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP006920MO CSB-EP006920MO CSB-BP006920MO CSB-MP006920MO CSB-EP006920MO-B	Recombinant Mouse Dickkopf-related protein 1 (Dkk1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli