Kdr

KDR，即Kinase Domain-containing Receptor，也被称为血管内皮生长因子受体2。KDR是一种跨膜受体酪氨酸激酶，主要在血管内皮细胞表达，参与调控血管生成和维护血管的完整性。其作用机制涉及与VEGF家族成员如VEGFA、VEGFC和VEGFD的结合，激活后引发受体二聚化和自身酪氨酸激酶活性，进而触发下游信号通路，如PI3K-Akt、Ras-Raf-MEK-ERK等，这些通路促进内皮细胞的增殖、迁移和血管通透性的增加。KDR在胚胎发育、组织修复、伤口愈合中发挥关键作用，是正常生理功能中必不可少的。同时，KDR的功能在多种病理状态下也至关重要，尤其是在肿瘤血管生成中，其过度激活与多种肿瘤的进展、转移密切相关，使其成为癌症治疗的重要靶点。此外，KDR还在某些心血管疾病中发挥作用，是研究和治疗相关疾病的潜在靶点。

热销产品

Recombinant Human Vascular endothelial growth factor receptor 2 (KDR), partial (CSB-EP012145HU)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

KDR Antibody (CSB-PA07279A0Rb)

验证数据

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA07279A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA07279A0Rb at dilution of 1:100

Kdr Antibody

Kdr Protein

Kdr ELISA Kit

Kdr Antibodies

Kdr for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA07279A0Rb	KDR Antibody	Human	ELISA, IHC
CSB-PA07279B0Rb	KDR Antibody, HRP conjugated	Human	ELISA
CSB-PA07279C0Rb	KDR Antibody, FITC conjugated	Human
CSB-PA07279D0Rb	KDR Antibody, Biotin conjugated	Human	ELISA
CSB-PA012145GA01HU	KDR Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA898056	Phospho-KDR (Tyr1175) Antibody	Human,Mouse,Rat	ELISA,IHC,IF
CSB-PA917275	Phospho-KDR (Tyr1214) Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA200726	Phospho-KDR (Tyr951) Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA905984	KDR (Ab-1175) Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA274392	KDR (Ab-1214) Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA920878	KDR (Ab-951) Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA444815	Phospho-KDR (Tyr1059) Antibody	Human,Mouse	ELISA,WB
CSB-PA070091	KDR (Ab-1059) Antibody	Human,Mouse	ELISA,WB
CSB-PA000527	Phospho-KDR (Y1175) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA000528	Phospho-KDR (Y1214) Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA002542	KDR Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA002543	KDR Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA009633	Phospho-KDR (Y951) Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA009634	Phospho-KDR (Y1059) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA009638	KDR Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA009642	KDR Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA490567	KDR Antibody	Human,Mouse,Rat	IHC,ELISA

Kdr Proteins

Kdr Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP012145MO CSB-EP012145MO CSB-BP012145MO CSB-MP012145MO CSB-EP012145MO-B	Recombinant Mouse Vascular endothelial growth factor receptor 2 (Kdr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Kdr Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP012145HU CSB-BP012145HU CSB-MP012145HU CSB-EP012145HU-B	Recombinant Human Vascular endothelial growth factor receptor 2 (KDR), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP012145HU	Recombinant Human Vascular endothelial growth factor receptor 2 (KDR), partial	E.coli

Kdr Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP012145RA CSB-EP012145RA CSB-BP012145RA CSB-MP012145RA CSB-EP012145RA-B	Recombinant Rat Vascular endothelial growth factor receptor 2 (Kdr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Kdr Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

产品货号	产品名称	来源
CSB-YP346773DXJ CSB-EP346773DXJ CSB-BP346773DXJ CSB-MP346773DXJ CSB-EP346773DXJ-B	Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2 (KDR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Kdr Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

产品货号	产品名称	来源
CSB-YP708034DIL CSB-EP708034DIL CSB-BP708034DIL CSB-MP708034DIL CSB-EP708034DIL-B	Recombinant Danio rerio Vascular endothelial growth factor receptor 2 (kdr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli