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OSM

OSM(Oncostatin M)是一种细胞因子蛋白。它是白细胞介素6(Interleukin-6,IL-6)家族中的成员之一,其结构是一种由单一多肽链组成的蛋白质,它与细胞表面上的受体结合,触发下游信号转导途径。 OSM在免疫调节、细胞增殖、分化和炎症等生理过程中发挥着重要作用。参与调控多种细胞类型的增殖和分化,包括肝细胞、胚胎干细胞、神经细胞等。在炎症性疾病中,OSM可以调节免疫细胞的活化和炎症反应。在肿瘤发展中,OSM可能促进肿瘤细胞的增殖和侵袭。 由于OSM在生理和病理过程中的重要作用,对其的研究对于理解免疫调节、炎症反应和肿瘤生物学等方面具有重要意义。同时,OSM也被认为是潜在的治疗靶点,针对OSM和其受体的治疗方法可能有助于调节疾病过程和发展新的治疗策略。

更多相关阅读:抑瘤素M (OSM): 白介素IL-6细胞因子家族成员,肿瘤、骨代谢、慢性炎症性等疾病的潜力靶点?

热销产品

OSM Recombinant Monoclonal Antibody CSB-RA017260MA1HU

验证数据

ELISA
CSB-RA017260MA1HU ELISA

The Binding Activity of Human OSM with Anti-OSM Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM (CSB-MP017260HU1) at 2 μg/mL can bind Anti-OSM recombinant antibody, the EC50 is 3.048-3.860 ng/mL

Recombinant Human Oncostatin-M(OSM),partial (Active) CSB-MP017260HU1

验证数据

SDS
CSB-MP017260HU1 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP017260HU1 ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM at 2μg/mL can bind Anti-OSM recombinant antibody (CSB-RA017260MA1HU),the EC50 is 3.048-3.860 ng/mL.

OSM Antibodies

OSM for Homo sapiens (Human)

OSM for Rattus norvegicus (Rat)

OSM Proteins

OSM Proteins for Homo sapiens (Human)

OSM Proteins for Bos taurus (Bovine)

OSM Proteins for Mus musculus (Mouse)

OSM Proteins for Rattus norvegicus (Rat)

OSM ELISA Kit

OSM ELISA Kit for Homo sapiens (Human)

OSM ELISA Kit for Mus musculus (Mouse)

OSM ELISA Kit for Rattus norvegicus (Rat)