OSM
OSM(Oncostatin M)是一种细胞因子蛋白。它是白细胞介素6(Interleukin-6,IL-6)家族中的成员之一,其结构是一种由单一多肽链组成的蛋白质,它与细胞表面上的受体结合,触发下游信号转导途径。 OSM在免疫调节、细胞增殖、分化和炎症等生理过程中发挥着重要作用。参与调控多种细胞类型的增殖和分化,包括肝细胞、胚胎干细胞、神经细胞等。在炎症性疾病中,OSM可以调节免疫细胞的活化和炎症反应。在肿瘤发展中,OSM可能促进肿瘤细胞的增殖和侵袭。 由于OSM在生理和病理过程中的重要作用,对其的研究对于理解免疫调节、炎症反应和肿瘤生物学等方面具有重要意义。同时,OSM也被认为是潜在的治疗靶点,针对OSM和其受体的治疗方法可能有助于调节疾病过程和发展新的治疗策略。
更多相关阅读:抑瘤素M (OSM): 白介素IL-6细胞因子家族成员,肿瘤、骨代谢、慢性炎症性等疾病的潜力靶点?
热销产品
● OSM Recombinant Monoclonal Antibody CSB-RA017260MA1HU
验证数据
The Binding Activity of Human OSM with Anti-OSM Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM (CSB-MP017260HU1) at 2 μg/mL can bind Anti-OSM recombinant antibody, the EC50 is 3.048-3.860 ng/mL
● Recombinant Human Oncostatin-M(OSM),partial (Active) CSB-MP017260HU1
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM at 2μg/mL can bind Anti-OSM recombinant antibody (CSB-RA017260MA1HU),the EC50 is 3.048-3.860 ng/mL.
OSM Antibodies
OSM for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA09694A0Rb | OSM Antibody | Human | ELISA, IHC |
CSB-PA09694C0Rb | OSM Antibody, FITC conjugated | Human | |
CSB-PA09694B0Rb | OSM Antibody, HRP conjugated | Human | ELISA |
CSB-PA244255 | OSM Antibody | Human | ELISA,WB,IHC |
CSB-PA934414 | OSM Antibody | Human | ELISA,IHC |
CSB-RA017260MA1HU | OSM Recombinant Monoclonal Antibody | Human | ELISA |
OSM for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA723970LA01RA | Osm Antibody | Rat | ELISA, IF |
CSB-PA723970LB01RA | Osm Antibody, HRP conjugated | Rat | ELISA |
CSB-PA723970LC01RA | Osm Antibody, FITC conjugated | Rat |
OSM Proteins
OSM Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP017260HU CSB-EP017260HU CSB-BP017260HU CSB-MP017260HU CSB-EP017260HU-B |
Recombinant Human Oncostatin-M (OSM), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-RP096944h | Recombinant Human Oncostatin-M (OSM), partial | E.coli |
CSB-AP002231HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
CSB-AP002241HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
CSB-AP002251HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
CSB-EP017260HU1 | Recombinant Human Oncostatin-M (OSM) | E.coli |
CSB-YP017260HUc7 | Recombinant Human Oncostatin-M (OSM), partial | Yeast |
CSB-MP017260HU1 | Recombinant Human Oncostatin-M (OSM), partial (Active) | Mammalian cell |
CSB-MP017260HU1d9 | Recombinant Human Oncostatin-M (OSM), partial | Mammalian cell |
OSM Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP017260BO CSB-EP017260BO CSB-BP017260BO CSB-MP017260BO CSB-EP017260BO-B |
Recombinant Bovine Oncostatin-M (OSM) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
OSM Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP017260MO CSB-EP017260MO CSB-BP017260MO CSB-MP017260MO CSB-EP017260MO-B |
Recombinant Mouse Oncostatin-M (Osm) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
OSM Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP723970RA | Recombinant Rat Oncostatin-M (Osm) | Yeast |
CSB-EP723970RA CSB-BP723970RA CSB-EP723970RA-B |
Recombinant Rat Oncostatin-M (Osm) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP723970RA | Recombinant Rat Oncostatin-M (Osm) | Mammalian cell |
CSB-EP723970RAb0 | Recombinant Rat Oncostatin-M (Osm) | E.coli |
OSM ELISA Kit
OSM ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E04696h | Human Oncostatin-M,OSM ELISA KIT | serum, plasma, cell culture supernates | 1.56 pg/mL |
OSM ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E04697m | Mouse Oncostatin-M,OSM ELISA KIT | serum, plasma, cell culture supernates, tissue homogenates | 0.78 pg/mL |
OSM ELISA Kit for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E07402r | Rat oncostatin M (OSM) ELISA kit | serum, plasma | 3.9 pg/mL |