Ppargc1a
PPARGC1A，即过氧化物酶体增殖物激活受体γ共激活剂1α，别名PGC-1α、PPRC1α。它是一种转录共激活因子，主要在心脏、骨骼肌、肝脏和肾脏等组织中高表达，而在大脑和胰腺中表达水平较低，在肠道和白色脂肪组织中表达水平非常低。PPARGC1A的作用机制涉及与多种核受体和转录因子相互作用，增强其转录活性，调节线粒体生物发生、能量代谢和热生成等过程。它参与昼夜节律和能量代谢的整合，激活与代谢相关的基因，如PDK4和PEPCK，调控生物钟基因的振荡表达。PPARGC1A是适应性产热和代谢重编程的关键调控因子，其表达水平受长期能量供应的控制，且在肥胖和高脂饮食环境下表达水平下降。PPARGC1A的功能异常与多种代谢性疾病有关，是治疗II型糖尿病、肥胖症、心肌病等代谢紊乱的潜在靶点。
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验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
货号：CSB-E11761h
规格：96T/48T
灵敏度：31.25 pg/mL
检测范围：125 pg/mL-8000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
Ppargc1a Antibodies
Ppargc1a for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA042134 | PPARGC1A Antibody | Human,Mouse,Rat | ELISA |
Ppargc1a Proteins
Ppargc1a Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP529139MO CSB-EP529139MO CSB-BP529139MO CSB-MP529139MO CSB-EP529139MO-B |
Recombinant Mouse Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (Ppargc1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ppargc1a Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP772944BO CSB-EP772944BO CSB-BP772944BO CSB-MP772944BO CSB-EP772944BO-B |
Recombinant Bovine Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ppargc1a Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP774721PI CSB-EP774721PI CSB-BP774721PI CSB-MP774721PI CSB-EP774721PI-B |
Recombinant Pig Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ppargc1a Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP871382HU CSB-BP871382HU CSB-MP871382HU CSB-EP871382HU-B |
Recombinant Human Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP871382HUa0 | Recombinant Human Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) | E.coli |
| CSB-EP871382HU | Recombinant Human Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) | E.coli |
Ppargc1a Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP889889RA CSB-EP889889RA CSB-BP889889RA CSB-MP889889RA CSB-EP889889RA-B |
Recombinant Rat Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (Ppargc1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ppargc1a ELISA Kit
Ppargc1a ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E11761h | Human peroxisome proliferative activated receptor gama coactivator 1 alpha,PPARGC1 ELISA Kit | serum, plasma, cell culture supernates, cell lysates | 31.25 pg/mL |
Ppargc1a ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL018425MO | Mouse Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) ELISA kit | serum, plasma, tissue homogenates | 5.86 pg/mL |
