SPOP
Speckle-type POZ protein is a protein in humans that is encoded by SPOP gene. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation.
SPOP Antibodies
SPOP for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA022601LA01HU | SPOP Antibody | Human | ELISA, IHC |
| CSB-PA022601LD01HU | SPOP Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA022601LC01HU | SPOP Antibody, FITC conjugated | Human |
SPOP Proteins
SPOP Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601HU CSB-EP022601HU CSB-BP022601HU CSB-MP022601HU CSB-EP022601HU-B |
Recombinant Human Speckle-type POZ protein (SPOP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPOP Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601MO CSB-EP022601MO CSB-BP022601MO CSB-MP022601MO CSB-EP022601MO-B |
Recombinant Mouse Speckle-type POZ protein (Spop) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPOP Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601XBF CSB-EP022601XBF CSB-BP022601XBF CSB-MP022601XBF CSB-EP022601XBF-B |
Recombinant Xenopus tropicalis Speckle-type POZ protein (spop) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPOP Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601DIL CSB-EP022601DIL CSB-BP022601DIL CSB-MP022601DIL CSB-EP022601DIL-B |
Recombinant Danio rerio Speckle-type POZ protein (spop) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPOP Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601BO CSB-EP022601BO CSB-BP022601BO CSB-MP022601BO CSB-EP022601BO-B |
Recombinant Bovine Speckle-type POZ protein (SPOP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SPOP Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP022601PYX CSB-EP022601PYX CSB-BP022601PYX CSB-MP022601PYX CSB-EP022601PYX-B |
Recombinant Pongo abelii Speckle-type POZ protein (SPOP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
