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TIRAP

Toll/interleukin-1 receptor domain-containing adapter protein is a protein in humans that is encoded by TIRAP gene. Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

TIRAP Antibodies

TIRAP for Homo sapiens (Human)

TIRAP Proteins

TIRAP Proteins for Homo sapiens (Human)

TIRAP Proteins for Mus musculus (Mouse)