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TMEFF2

TMEFF2(Transmembrane Protein with EGF-like and Two Follistatin-like domains 2)是一种跨膜蛋白,在人类组织中广泛表达。其结构包括一个信号肽、一个EGF样结构域和两个Follistatin样结构域。TMEFF2在多种生理和病理过程中发挥重要作用,包括胚胎发育、神经发育、神经保护和肿瘤发生等。

研究表明,TMEFF2在多种癌症中具有不同的作用。例如,在乳腺癌、前列腺癌和肺癌等多种肿瘤中,TMEFF2的表达水平明显降低,与肿瘤发生和进展密切相关。另外,一些研究表明TMEFF2可能具有抗肿瘤的作用,例如在胃癌中表达TMEFF2的患者存活期更长。因此,TMEFF2被认为是一个重要的癌症治疗靶点,对其研究和开发相关药物具有重要意义。

更多TMEFF2相关阅读:表皮生长因子TMEFF2:肿瘤特异性或甲基化标志物,双功能靶点蕴藏新机会!

热销产品

Recombinant Human TMEFF2, partial (Active) CSB-MP883439HU

验证数据

High Purity Validated by SDS-PAGE

The purity was greater than 95% as determined by SDS-PAGE.

Excellent Bioactivity Validated by Functional ELISA

Immobilized Human TMEFF2 at 2 μg/mL can bind Anti-TMEFF2 recombinant antibody (CSB-RA883439MA1HU), the EC50 is 2.129-2.956 ng/mL.

Recombinant Macaca fascicularis Jacalin-type lectin domain-containing protein (Active) CSB-MP4727MOV

验证数据

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ZG16B at 2μg/mL can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU), the EC50 is 20.15-28.98 ng/mL.

TMEFF2 Antibodies

TMEFF2 for Homo sapiens (Human)

TMEFF2 Proteins

TMEFF2 Proteins for Bos taurus (Bovine)

TMEFF2 Proteins for Pongo abelii (Sumatran orangutan)

TMEFF2 Proteins for Homo sapiens (Human)

TMEFF2 Proteins for Mus musculus (Mouse)