TWIST1
TWIST1,即扭曲螺旋转录因子1,别名TWIST、TWISTL1等。它是一种由TWIST1基因编码的转录因子,属于基本螺旋-环-螺旋(bHLH)超家族成员,在多种组织中表达。TWIST1的作用机制主要是通过结合到特定DNA序列上的E-box元件,调控下游基因的表达,影响细胞的增殖、分化和迁移。TWIST1的异常表达与多种疾病有关,尤其是在癌症中,TWIST1的高表达与肿瘤的侵袭性、转移和预后不良相关。TWIST1能够促进上皮-间充质转化(EMT),增强肿瘤细胞的侵袭和转移能力。因此,TWIST1是肿瘤研究和治疗中的一个潜在靶点。
热销产品
TWIST1 Antibody (CSB-PA944996)
验证数据
Western blot analysis of extracts from JK, Raji and HL-60 cells using Twist1 Antibody.
Twist1 Antibody staining Twist in Mouse pancreatic cancer tissue sections by Immunohistochemistry
TWIST1 Antibodies
TWIST1 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA025358GA01HU | TWIST1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA944996 | TWIST1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA245152 | TWIST1 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA084858 | TWIST1 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA025358LA01HU | TWIST1 Antibody | Human | ELISA, WB |
CSB-PA025358LB01HU | TWIST1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA025358LC01HU | TWIST1 Antibody, FITC conjugated | Human | |
CSB-PA025358LD01HU | TWIST1 Antibody, Biotin conjugated | Human | ELISA |
TWIST1 Proteins
TWIST1 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP613599HU CSB-EP613599HU CSB-BP613599HU CSB-MP613599HU CSB-EP613599HU-B |
Recombinant Human Twist-related protein 1 (TWIST1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |