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Ttr

TTR(Transthyretin),也被称为前甲状腺素运载蛋白(prealbumin),是一种在体内运输甲状腺激素(thyroxine)和维生素A的四聚体蛋白质,由四个相同的亚基组成。这四个亚基结合在一起,形成一个稳定的结构。主要用于运输甲状腺激素,特别是甲状腺素(T4)和三碘甲状腺原氨酸(T3)以及维生素A的运输。 TTR异常与一种遗传性淀粉样多发性神经病(Hereditary Transthyretin Amyloidosis,hATTR)相关。在hATTR中,TTR蛋白质会发生异常聚集,形成淀粉样斑块,最终导致神经系统和器官功能受损。因此,研究TTR的异常和与之相关的疾病机制对于了解hATTR以及开发相关治疗方法非常重要。

更多相关阅读:TTR:淀粉样变性关键蛋白,多款创新疗法用于ATTR-CM和ATTR-PN罕见病!

热销产品

Recombinant Human Transthyretin(TTR) (Active) CSB-MP025270HUh6

验证数据

SDS
CSB-MP025270HUh6 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP025270HUh6

Activity: Measured by its binding ability in a functional ELISA. Immobilized RBP4 (CSB-MP019483HU) at 5 μg/ml can bind human TTR, the EC50 of human TTR protein is 284.7-391.7 ng/ml.

Recombinant Mouse Transthyretin(Ttr) (Active) CSB-MP025270MO

验证数据

SDS
CSB-MP025270MO SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP025270MO

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Ttr at 5 μg/ml can bind Mouse Rbp4 (CSB-MP4018MO), theEC50 is 17.06-26.23 ng/mL.

Ttr Antibodies

Ttr for Homo sapiens (Human)

Ttr for Mus musculus (Mouse)

Ttr for Macaca fascicularis

Ttr Proteins

Ttr Proteins for Ovis aries (Sheep)

Ttr Proteins for Gallus gallus (Chicken)

Ttr Proteins for Sus scrofa (Pig)

Ttr Proteins for Oryctolagus cuniculus (Rabbit)

Ttr Proteins for Bos taurus (Bovine)

Ttr Proteins for Xenopus laevis (African clawed frog)

Ttr Proteins for Crocodylus porosus (Crocodile)

Ttr Proteins for Sorex araneus (Eurasian common shrew) (European shrew)

Ttr Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Ttr Proteins for Trachydosaurus rugosus (Shingleback lizard) (Tiliqua rugosus)

Ttr Proteins for Macropus eugenii (Tammar wallaby)

Ttr Proteins for Sminthopsis macroura (Stripe-faced dunnart)

Ttr Proteins for Monodelphis domestica (Gray short-tailed opossum)

Ttr Proteins for Petaurus breviceps (Australian sugar glider)

Ttr Proteins for Homo sapiens (Human)

Ttr Proteins for Rattus norvegicus (Rat)

Ttr Proteins for Pseudomonas syringae pv. tabaci

Ttr Proteins for Pongo abelii (Sumatran orangutan)

Ttr Proteins for Pan troglodytes (Chimpanzee)

Ttr Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Ttr Proteins for Erinaceus europaeus (Western European hedgehog)

Ttr Proteins for Macropus giganteus (Eastern gray kangaroo)

Ttr Proteins for Mus musculus (Mouse)

Ttr Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Ttr ELISA Kit

Ttr ELISA Kit for Rattus norvegicus (Rat)

Ttr ELISA Kit for Bos taurus (Bovine)

Ttr ELISA Kit for Homo sapiens (Human)

Ttr ELISA Kit for Mus musculus (Mouse)