pfo
Perfringolysin O (PFO)是由肉毒梭菌（Clostridium perfringens）产生的毒素。其结构是一个大的单亚单位蛋白，具有约497个氨基酸，含有多个β-折叠和α螺旋结构。PFO主要通过与细胞膜中的胆固醇结合，形成聚合物，并形成可通透的孔道，导致细胞膜的破坏和溶解。这种溶孔作用会破坏细胞的完整性，导致溶解和细胞死亡。PFO主要通过胆固醇结合并引发细胞膜的溶解，导致细胞内外离子平衡失调，从而影响细胞的生存和功能。PFO和其变体可以用作生物学研究中的细胞膜溶解工具，用于探究细胞膜通透性和细胞膜受损的影响。在肉毒梭菌感染的情况下，PFO被认为是该菌致病性的重要因素之一，它参与了细胞的溶解和组织损伤，因此在了解和研究感染机制、药物开发等方面有一定的应用价值。
热销产品
Recombinant Clostridium perfringens Perfringolysin O (pfo)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP314820CMB could indicate that this peptide derived from E.coli-expressed Clostridium perfringens (strain 13 / Type A) pfo.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP314820CMB could indicate that this peptide derived from E.coli-expressed Clostridium perfringens (strain 13 / Type A) pfo.
pfo Antibodies
pfo for Clostridium perfringens
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA314820HA01CMB | pfo Antibody | Clostridium perfringens | ELISA, WB |
| CSB-PA314820HB01CMB | pfo Antibody, HRP conjugated | Clostridium perfringens | ELISA |
| CSB-PA314820HC01CMB | pfo Antibody, FITC conjugated | Clostridium perfringens | |
| CSB-PA314820HD01CMB | pfo Antibody, Biotin conjugated | Clostridium perfringens | ELISA |
pfo Proteins
pfo Proteins for Clostridium perfringens
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP314820CMB CSB-BP314820CMB CSB-MP314820CMB CSB-EP314820CMB-B |
Recombinant Clostridium perfringens Perfringolysin O (pfo) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
pfo Proteins for Clostridium perfringens (strain 13 / Type A)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP314820CMB | Recombinant Clostridium perfringens Perfringolysin O (pfo) | E.coli |
