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CLEC2B Antibody

  • 中文名称：
    CLEC2B兔多克隆抗体
  • 货号：
    CSB-PA272000
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA272000(CLEC2B Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q92478
  • 基因名：
    CLEC2B
  • 别名：
    CLEC2B antibody; AICL antibody; CLECSF2 antibody; IFNRG1C-type lectin domain family 2 member B antibody; Activation-induced C-type lectin antibody; C-type lectin superfamily member 2 antibody; IFN-alpha-2b-inducing-related protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human CLEC2B
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Review of C-type lectin-like receptor 2 and podoplanin interactions [review] PMID: 27960039
    2. Data suggest that vascular smooth muscle cells (VSMCs) stimulate platelets through platelet receptor CLEC-2, possibly leading to thrombus formation after plaque erosion. PMID: 26418160
    3. Lipid rafts do not directly contribute to CLEC-2 receptor activation in platelets. PMID: 25462818
    4. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL axis. PMID: 23929856
    5. expressed in primary liver cancers PMID: 20663776
    6. NKp80 is expressed on a highly responsive subset of effector memory CD8 T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL-expressing cells. PMID: 18922855

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  • 亚细胞定位：
    Membrane; Single-pass type II membrane protein.
  • 组织特异性：
    Expressed preferentially in lymphoid tissues, and in most hematopoietic cell types.
  • 数据库链接：

    HGNC: 2053

    OMIM: 603242

    KEGG: hsa:9976

    STRING: 9606.ENSP00000228438

    UniGene: Hs.85201