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EXOC5 Antibody

  • 中文名称:
    EXOC5兔多克隆抗体
  • 货号:
    CSB-PA007883GA01HU
  • 规格:
    ¥3,900
  • 其他:

产品详情

  • Uniprot No.:
    O00471
  • 基因名:
    EXOC5
  • 别名:
    EXOC5 antibody; SEC10 antibody; SEC10L1Exocyst complex component 5 antibody; Exocyst complex component Sec10 antibody; hSec10 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse,Rat
  • 免疫原:
    Human EXOC5
  • 免疫原种属:
    Homo sapiens (Human)
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB,IF
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
  • 基因功能参考文献:
    1. These data confirm that the exocyst is preferentially involved in basolateral protein translation and translocation, and may well act through the phosphorylation of Sec61beta. PMID: 23037926
    2. Suggest that the exocyst sec10, acting through EGFR, endocytosis, and the MAPK pathway is a candidate therapeutic target for acute kidney injury. PMID: 25298525
    3. Exocyst Sec10 overexpression reduces damage to tubular epithelial barriers caused by hydrogen peroxide and speeds the recovery of normal epithelial barrier function after such an injury. PMID: 20053792
    4. Data show that GTP-bound ARF6 interacts with Sec10, a subunit of the exocyst complex involved in docking of vesicles with the plasma membrane. PMID: 14662749
    5. The exocyst protein Sec10 regulates primary ciliogenesis. PMID: 19297529

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  • 亚细胞定位:
    Cytoplasm. Midbody.
  • 蛋白家族:
    SEC10 family
  • 组织特异性:
    Ubiquitous.
  • 数据库链接:

    HGNC: 10696

    OMIM: 604469

    KEGG: hsa:10640

    STRING: 9606.ENSP00000389934

    UniGene: Hs.743987