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FTSI Antibody

  • 中文名称：
    FTSI兔多克隆抗体
  • 货号：
    CSB-PA364923XA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: FTSI antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 32.4 kDa
      Observed band size: 38 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P0AD68
  • 基因名：
    FTSI
  • 别名：
    Peptidoglycan D,D-transpeptidase FtsI (EC 3.4.16.4) (Essential cell division protein FtsI) (Murein transpeptidase) (Penicillin-binding protein 3) (PBP-3) (Peptidoglycan synthase FtsI) ftsI pbpB b0084 JW0082
  • 反应种属：
    Shigella flexneri
  • 免疫原：
    Recombinant Escherichia coli (strain K12) FTSI protein
  • 免疫原种属：
    Escherichia coli (strain K12)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN.
  • 基因功能参考文献：
    1. A beta-lactam MIC of 8 mug/ml was reported for the three combinations against one Escherichia coli isolate with an unusual TIPY insertion following Tyr344 in penicillin-binding protein 3 (PBP 3) as the result of gene duplication. PMID: 28559260
    2. In this work the s show direct interactions between FtsW and PBP3 in vivo and in vitro by FRET (Forster resonance energy transfer) and co-immunoprecipitation experiments. PMID: 20847002
    3. Alanine-scanning mutagenesis of the Transmembrane helix identified several residues important for septal localization. PMID: 15601716
    4. direct interaction between a class B PBP (PBP3) and a class A PBP (PBP1B) in vitro and in vivo, indicating that different murein synthases might act in concert to enlarge the murein sacculus during cell division PMID: 16803586
    5. FtsI is associated in a hierarchical set of protein complexes and its assembly can occur independently of 'upstream' proteins. PMID: 16824093
    6. Data show that PBP3 interact with MtgA and help MtgA's role in peptidoglycan assembly during the cell cycle. PMID: 18165305

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  • 亚细胞定位：
    Cell inner membrane; Single-pass membrane protein; Periplasmic side.
  • 蛋白家族：
    Transpeptidase family, FtsI subfamily
  • 数据库链接：

    KEGG: ecj:JW0082

    STRING: 316385.ECDH10B_0066