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GADL1 Antibody

  • 中文名称：
    GADL1兔多克隆抗体
  • 货号：
    CSB-PA009166GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q6ZQY3
  • 基因名：
    GADL1
  • 别名：
    GADL1Acidic amino acid decarboxylase GADL1 antibody; Aspartate 1-decarboxylase antibody; ADC antibody; HuADC antibody; EC 4.1.1.11 antibody; Cysteine sulfinic acid decarboxylase antibody; CSADC antibody; HuCSADC antibody; EC 4.1.1.29 antibody; Glutamate decarboxylase-like protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human GADL1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate.
  • 基因功能参考文献：
    1. No difference in GADL1 expression was observed among lymphoblastoid cells from excellent-responders, non-responders or controls. Furthermore, lithium did not induce significant changes in GADL1 expression levels after 4 or 8 days. These results did not support an association of GADL1 expression in the determination of a lithium response in BD patients. PMID: 28214779
    2. taurine biosynthesis in vertebrates involves two structurally related PLP-dependent decarboxylases (cysteine sulfinic acid decarboxylase and glutamic acid decarboxylase like 1) PMID: 26327310
    3. The study did not identify a major relationship between the GADL1 polymorphisms and lithium response in an Indian population. PMID: 25415457
    4. Genetic variations in GADL1 are associated with the response to lithium maintenance treatment for bipolar I disorder in patients of Han Chinese descent. PMID: 24369049
  • 蛋白家族：
    Group II decarboxylase family
  • 组织特异性：
    Expressed very weakly in neurons and not detected in astrocytes, brain or liver.
  • 数据库链接：

    HGNC: 27949

    OMIM: 615601

    KEGG: hsa:339896

    STRING: 9606.ENSP00000282538

    UniGene: Hs.657052