RAB40B Antibody
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货号:CSB-PA019204GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q12829
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基因名:RAB40B
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别名:RAB40B antibody; SEC4L antibody; Ras-related protein Rab-40B antibody; SOCS box-containing protein RAR antibody; Protein Rar antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human RAB40B
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,IHC
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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基因功能参考文献:
- This is the first study that identifies a new Rab40b-Tks5- and miR-204-dependent invadopodia transport pathway that regulates MMP2 and MMP9 secretion, and extracellular matrix remodeling during cancer progression. PMID: 27789576
- High expression level of Rab40b was significantly correlated with gastric cancer invasion and lymph node metastasis. PMID: 25790780
- Rab40b mediates trafficking of MMP2/9 during invadopodia formation and metastasis of breast cancer cells. PMID: 23902685
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亚细胞定位:Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族:Small GTPase superfamily, Rab family
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数据库链接:
HGNC: 18284
KEGG: hsa:10966
STRING: 9606.ENSP00000461785
UniGene: Hs.484068
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