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RAB40B Antibody

  • 货号：
    CSB-PA615534LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA615534LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RAB40B Polyclonal antibody
  • Uniprot No.：
    Q12829
  • 基因名：
    RAB40B
  • 别名：
    RAB40B antibody; SEC4L antibody; Ras-related protein Rab-40B antibody; SOCS box-containing protein RAR antibody; Protein Rar antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ras-related protein Rab-40B protein (1-278AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RAB40B Antibody (CSB-PA615534LA01HU)，的标记方式是Non-conjugated。对于RAB40B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA615534LB01HU RAB40B Antibody, HRP conjugated ELISA
    FITC CSB-PA615534LC01HU RAB40B Antibody, FITC conjugated
    Biotin CSB-PA615534LD01HU RAB40B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 基因功能参考文献：
    1. This is the first study that identifies a new Rab40b-Tks5- and miR-204-dependent invadopodia transport pathway that regulates MMP2 and MMP9 secretion, and extracellular matrix remodeling during cancer progression. PMID: 27789576
    2. High expression level of Rab40b was significantly correlated with gastric cancer invasion and lymph node metastasis. PMID: 25790780
    3. Rab40b mediates trafficking of MMP2/9 during invadopodia formation and metastasis of breast cancer cells. PMID: 23902685
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 数据库链接：

    HGNC: 18284

    KEGG: hsa:10966

    STRING: 9606.ENSP00000461785

    UniGene: Hs.484068