Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. RAB40B Antibody

RAB40B Antibody

  • 货号：
    CSB-PA006749
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using Rab 40B Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q12829
  • 基因名：
    RAB40B
  • 别名：
    RAB40B antibody; SEC4L antibody; Ras-related protein Rab-40B antibody; SOCS box-containing protein RAR antibody; Protein Rar antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Rab 40B.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 基因功能参考文献：
    1. This is the first study that identifies a new Rab40b-Tks5- and miR-204-dependent invadopodia transport pathway that regulates MMP2 and MMP9 secretion, and extracellular matrix remodeling during cancer progression. PMID: 27789576
    2. High expression level of Rab40b was significantly correlated with gastric cancer invasion and lymph node metastasis. PMID: 25790780
    3. Rab40b mediates trafficking of MMP2/9 during invadopodia formation and metastasis of breast cancer cells. PMID: 23902685
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 数据库链接：

    HGNC: 18284

    KEGG: hsa:10966

    STRING: 9606.ENSP00000461785

    UniGene: Hs.484068