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世界防治疟疾日:
携手抗“疟”,共筑健康未来

世界防治疟疾日

每年的4月25日是“世界防治疟疾日”(World Malaria Day),这一天旨在唤起全球对抗疟疾的意识,提高人们对这一疾病的认知,加强合作,推动实现全球疟疾零负担的愿景。作为全球范围内最为致命的传染病之一,疟疾每年造成全球几十万人的死亡,尤其对儿童和孕妇构成严重威胁。因此,这一天不仅是纪念抗击疟疾的斗争历程,更是为了倡导科学进步,强化预防措施,提高诊断和治疗水平。今年的主题是“防止疟疾再传播,持续巩固消除成果”。

疟疾(Malaria)是由疟原虫属寄生虫引起的一种可致命的传染病,当携带疟原虫的雌性按蚊叮咬人体时,会将疟原虫的孢子体注入人体血液中,这些孢子体随后侵入肝细胞发育成裂殖体,并进一步侵犯红细胞,引发周期性的发热、寒战、出汗和头痛等症状。按照感染人类的不同疟原虫种类的不同,将疟疾分为日疟、卵形疟、三日疟和恶性疟等类型。

目前,疟疾治疗通常是根据不同类型的疟疾针对性的选用药物治疗,无需手术。在药物研发方面,鉴于疟疾对传统抗疟药物如氯喹和磺胺多辛-乙胺嘧啶等的耐药性增加,科研人员正致力于寻找和验证新的药物靶点。其中,针对疟原虫生命周期特定阶段的药物设计受到特别关注,比如抑制疟原虫在肝脏期发育的药物,或是阻止疟原虫在红细胞内繁殖的化合物。在过去的几年里,单克隆抗体疗法也展现出潜力,能够特异性地结合并清除疟原虫,减少疟疾的传播和发病。

此外,疟疾疫苗的研发一直是全球健康领域的热点。尽管首个获批用于儿童的RTS,S/AS01(商品名Mosquirix)疟疾疫苗已经在部分高风险地区投入使用,但它提供的保护效力有限且不持久。因此,科研人员正在探索更为有效的疫苗策略,包括基于蛋白质的多表位疫苗、RNA疫苗及DNA疫苗等,力求提升疫苗诱导的免疫反应强度和持久性。

j9九游会登录入口首页生物长期致力于为科研工作者提供高质量的蛋白、抗体、ELISA试剂盒等工具类科研试剂产品,鉴于疟疾研究的重要性与迫切性,在此特别整理了一系列与疟疾研究相关的20余种热门靶点及相关试剂产品列举如下,供您选择:

疟疾研究相关ELISA试剂盒:

产品名称 货号 靶点 检测范围 灵敏度
大鼠血管紧张素转化酶2(ACE2)酶联免疫试剂盒 CSB-E14308r ACE2 0.02 ng/ml - 20 ng/ml 0.02 ng/ml
人血管紧张素转化酶2(ACE2)酶联免疫试剂盒 CSB-E04489h ACE2 0.156 ng/mL-10 ng/mL 0.039 ng/mL
小鼠血管紧张素转化酶2(ACE2)酶联免疫试剂盒 CSB-E17204m ACE2 6.25 pg/mL-400 pg/mL 1.56 pg/mL
人RACα丝氨酸/苏氨酸蛋白激酶(AKT1)酶联免疫试剂盒 CSB-EL001553HU AKT1 0.312 ng/mL-20 ng/mL 0.078 ng/mL
牛白蛋白(ALB)酶联免疫试剂盒 CSB-E08664b ALB 0.313 μg/mL-80 μg/mL 0.148 μg/mL
小鼠白蛋白酶联免疫试剂盒 CSB-E13878m ALB 0.781 μg/mL-200 μg/mL 0.110 μg/mL
犬白蛋白(Alb)酶联免疫试剂盒 CSB-E15757c ALB 0.273 μg/mL-35 μg/mL 0.266 μg/mL
绵羊白蛋白酶联免疫试剂盒 CSB-E15839Sh ALB 350 μg/mL-21.88 μg/mL 5.5 μg/mL
马白蛋白酶联免疫试剂盒 CSB-E16205Hs ALB 1.25 μg/mL-80 μg/mL 1.247 μg/mL
猪白蛋白酶联免疫试剂盒 CSB-E16207p ALB 0.03 μg/mL-7000 μg/mL 0.03 μg/mL
山羊白蛋白(Alb)酶联免疫试剂盒 CSB-E15758G ALB 0.17 μg/mL-350 μg/mL 0.17 μg/mL
豚鼠白蛋白(ALB)酶联免疫试剂盒 CSB-E15765Gp ALB 0.156 μg/mL-10 μg/mL 0.09 μg/mL
兔白蛋白酶联免疫试剂盒 CSB-E16204Rb ALB 0.273 μg/mL-70 μg/mL 0.117 μg/mL
人CD4分子(CD4)酶联免疫试剂盒 CSB-E08956h CD4 0.625 ng/mL-40 ng/mL 0.156 ng/mL
大鼠CD4分子(CD4)酶联免疫试剂盒 CSB-E12928r CD4 0.78 U/mL-50 U/mL 0.195 U/mL
鸡CD4分子(CD4)酶联免疫试剂盒 CSB-E13114C CD4 3.125 ng/mL-800 ng/mL 3.125 ng/mL
人CD8分子(CD8)酶联免疫试剂盒 CSB-E12707h CD8A 62.5 U/mL-4000 U/mL 15.6 U/mL
小鼠C反应蛋白(CRP)酶联免疫试剂盒 CSB-E07923m(1) CRP 5 ng/mL-4000 ng/mL 5 ng/mL
兔子C反应蛋白(CRP)酶联免疫试剂盒 CSB-E06847Rb CRP 7.8 pg/mL-2000 pg/mL 2 pg/mL
大鼠C反应蛋白(CRP)酶联免疫试剂盒 CSB-E07922r CRP 31.25 ng/mL-2000 ng/mL 7.81 ng/mL

疟疾研究相关重组蛋白:

产品名称 货号 靶点 来源 蛋白标签
Recombinant Mouse Serum albumin (Alb) CSB-BP001561MO Alb Baculovirus C-terminal 9xHis-tagged
Recombinant Macaca mulatta Interleukin-10 (IL10) CSB-BP011580MOW IL10 Baculovirus N-terminal 10xHis-tagged and C-terminal myc-tagged
Recombinant Macaca mulatta Interleukin-10 (IL10) CSB-BP011580MOWd7 IL10 Baculovirus C-terminal 10xHis-tagged
Recombinant Marmota monax Tumor necrosis factor (TNF), partial CSB-BP523593MQG TNF Baculovirus N-terminal 10xHis-tagged
Recombinant Human T-cell surface glycoprotein CD4 (CD4), partial CSB-CF004935HU1 CD4 in vitro E.coli expression system N-terminal 6xHis-tagged
Recombinant Human RAC-alpha serine/threonine-protein kinase (AKT1) CSB-EP001553HU AKT1 E.coli N-terminal GST-tagged
Recombinant Dog Serum albumin (ALB) CSB-EP001561DO ALB E.coli N-terminal 6xHis-tagged
Recombinant Macaca fascicularis albumin (ALB) CSB-EP001561MOV ALB E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial CSB-EP004966BO CD8A E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial CSB-EP004966HU CD8A E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Human Epidermal growth factor receptor (EGFR), partial CSB-EP007479HU3 EGFR E.coli N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU ERBB2 E.coli N-terminal 6xHis-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU1 ERBB2 E.coli N-terminal 6xHis-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU3 ERBB2 E.coli N-terminal 10xHis-tagged and C-terminal Myc-tagged
Recombinant Human Alanine aminotransferase 1 (GPT) CSB-EP009864HU GPT E.coli N-terminal 6xHis-tagged
Recombinant Chicken Interferon gamma (IFNG) CSB-EP011050CH IFNG E.coli N-terminal GST-tagged
Recombinant Human Interferon gamma (IFNG) CSB-EP011050HU IFNG E.coli N-terminal 6xHis-tagged
Recombinant Mouse Interferon gamma (Ifng), partial CSB-EP011050MO1 Ifng E.coli N-terminal 6xHis-tagged
Recombinant Marmota monax Interferon gamma (IFNG) CSB-EP011050MQG IFNG E.coli N-terminal 6xHis-tagged
Recombinant Rat Interferon gamma (Ifng) CSB-EP011050RA Ifng E.coli N-terminal GST-tagged

疟疾研究相关抗体:

● 重组抗体:

产品名称 货号 靶点 反应种属 应用范围
Phospho-AKT1 (T450) Recombinant Monoclonal Antibody CSB-RA001553A450phHU AKT1 Human ELISA, WB
Phospho-AKT1 (Ser473) Recombinant Monoclonal Antibody CSB-RA001553A473phHU AKT1 Human ELISA, WB, IHC, IF, IP
AKT1 Recombinant Monoclonal Antibody CSB-RA917625A0HU AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
ALB Recombinant Monoclonal Antibody CSB-RA264109A0HU ALB Human ELISA, FC
CD4 Recombinant Monoclonal Antibody CSB-RA004935A0HU CD4 Human ELISA, WB, IHC
CD8A Recombinant Monoclonal Antibody CSB-RA934881A0HU CD8A Human ELISA, WB, IHC, IP
CRP Recombinant Monoclonal Antibody CSB-RA988767A0HU CRP Human ELISA, IHC
Phospho-EGFR (Y1092) Recombinant Monoclonal Antibody CSB-RA007479A1092phHU EGFR Human ELISA, WB
Phospho-EGFR (Y1068) Recombinant Monoclonal Antibody CSB-RA007479A1068phHU EGFR Human ELISA, WB
EGFR Recombinant Monoclonal Antibody CSB-RA159341A0HU EGFR Human ELISA, WB, IHC, IF, FC
EGFR Recombinant Monoclonal Antibody CSB-RA794061A0HU EGFR Human ELISA, WB, IHC
EGFR Recombinant Monoclonal Antibody CSB-RA159341MA1HU EGFR Human ELISA, IHC, FC
ERBB2 Recombinant Monoclonal Antibody CSB-RA260392A0HU ERBB2 Human ELISA, IHC, IF
ERBB2 Recombinant Monoclonal Antibody CSB-RA007763MA1HU ERBB2 Human ELISA
Phospho-ERBB2 (Y1139) Recombinant Monoclonal Antibody CSB-RA588766A0HU ERBB2 Human ELISA, IHC, IF
ERBB2 Recombinant Monoclonal Antibody CSB-RA007763MA2HU ERBB2 Human ELISA, IHC
IL10 Recombinant Monoclonal Antibody CSB-RA011580A0HU IL10 Human ELISA
IL6 Recombinant Monoclonal Antibody CSB-RA011664MA1HU IL6 Human ELISA
INS Recombinant Monoclonal Antibody CSB-RA584163A0HU INS Human ELISA, IHC
Phospho-MTOR (S2481) Recombinant Monoclonal Antibody CSB-RA008968A2481phHU MTOR Human ELISA, WB, IF
Phospho-MTOR (S2448) Recombinant Monoclonal Antibody CSB-RA008968A2448phHU MTOR Human ELISA, WB, IHC, IF

● 单克隆抗体:

产品名称 货号 靶点 反应种属 应用范围
AKT1 Monoclonal Antibody CSB-MA011037 AKT1 Human,Mouse,Pig,Rat ELISA, WB
ALB Monoclonal Antibody CSB-MA076752 ALB Human ELISA, WB, IHC
CD4 Monoclonal Antibody CSB-MA000228 CD4 Human,Mouse,Rat ELISA, IHC
CD4 Monoclonal Antibody,Purified CSB-MA783233 CD4 Human ELISA, FC
CD8A Monoclonal Antibody,Purified CSB-MA927984 CD8A Human ELISA, FC
CRP Monoclonal Antibody CSB-MA027411E0m CRP Human ELISA, IHC
CXCL8 Monoclonal Antibody CSB-MA083271A0m CXCL8 Human ELISA, IHC
EGFR Monoclonal Antibody CSB-MA000199 EGFR Human ELISA, WB, IHC, IF
EGFR Monoclonal Antibody CSB-MA000293 EGFR Human ELISA, WB
ERBB2 Monoclonal Antibody CSB-MA000200 ERBB2 Human,Mouse,Rat ELISA, WB, IHC
ERBB2 Monoclonal Antibody CSB-MA000237 ERBB2 Human ELISA, WB
ERBB2 Monoclonal Antibody CSB-MA172796 ERBB2 Human ELISA, WB, IHC
IFNG Monoclonal Antibody CSB-MA065241A0m IFNG Human ELISA, IHC
IL6 Monoclonal Antibody CSB-MA067571A0m IL6 Human ELISA, WB, IHC
TNF Monoclonal Antibody CSB-MA084771A0m TNF Bovine ELISA
TNF Monoclonal Antibody CSB-MA080271 TNF Human,Mouse,Rat ELISA, WB, IHC
TNF Monoclonal Antibody CSB-MA080272 TNF Human,Mouse,Rat ELISA, WB, IHC

● 多克隆抗体:

产品名称 货号 靶点 反应种属 应用范围
ACE2 Antibody CSB-PA866317LA01HU ACE2 Human ELISA, IHC, IF
Ace2 Antibody CSB-PA688690OA01RA Ace2 Rat ELISA, WB
ACE2 Antibody CSB-PA040178 ACE2 Human, Mouse ELISA, WB
ACE2 Antibody CSB-PA001150GA01HU ACE2 Human, Mouse, Rat ELISA, WB
ACE2 Antibody CSB-PA111496 ACE2 Human ELISA, IHC
ACE2 Antibody CSB-PA025395 ACE2 Human, Mouse, Rat ELISA, IHC
ACE2 Antibody CSB-PA445794 ACE2 Human, Mouse, Rat ELISA, IHC
AKT1 Antibody CSB-PA15905A0Rb AKT1 Human ELISA, WB, IHC, IF, IP
AKT1 Antibody CSB-PA000852 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
Phospho-AKT1 (S124) Antibody CSB-PA008118 AKT1 Human, Mouse, Rat ELISA, WB, IHC
Phospho-AKT1 (T72) Antibody CSB-PA008120 AKT1 Human, Mouse, Rat ELISA, WB, IHC
AKT1 Antibody CSB-PA008122 AKT1 Human, Mouse, Rat ELISA, IHC
AKT1 Antibody CSB-PA080256 AKT1 Human, Mouse, Rat WB
Phospho-AKT1 (S129) Antibody CSB-PA000645 AKT1 Human, Mouse, Rat ELISA, WB
Phospho-AKT1 (T308) Antibody CSB-PA000657 AKT1 Human, Mouse, Rat ELISA, WB
Phospho-AKT1 (S473) Antibody CSB-PA000732 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
AKT1 Antibody CSB-PA000851 AKT1 Human, Mouse, Rat, Monkey ELISA, WB, IHC, IF
Phospho-AKT1 (S246) Antibody CSB-PA000465 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
Phospho-AKT1 (T450) Antibody CSB-PA000468 AKT1 Human, Mouse, Rat ELISA, WB, IHC
Phospho-AKT1 (Y326) Antibody CSB-PA000649 AKT1 Human, Mouse, Rat ELISA, WB