Il1a
IL1A，即白细胞介素1α，别名IL-1α、Hematopoietin-1、Lymphocyte-Activating Factor (LAF)、Endogenous Pyrogen (EP)、IL1F1等。它是一种由IL1A基因编码的多效性细胞因子，主要由活化的巨噬细胞、中性粒细胞、上皮细胞和内皮细胞产生 。IL1A的作用机制涉及其前体蛋白在细胞内的转录因子功能以及成熟形式在细胞外的信号传导作用。IL1A前体在细胞核内促进基因表达，调控细胞生长和分化。成熟形式的IL1A通过与细胞表面的IL-1受体IL1R1结合，触发信号传导复合物的形成，激活NF-kappa-B和MAPK通路，从而引发炎症反应和免疫应答 。在生物学意义上，IL1A在机体的炎症反应、免疫调节以及与多种疾病的关联中发挥关键作用。它参与机体抗微生物感染、无菌炎症、肿瘤相关疾病以及自发炎症的调节。IL1A的异常表达与多种疾病有关，包括Fabry病、Schnitzler综合征、多种自身免疫性疾病、血液肿瘤和肺部疾病等。因此，IL1A是炎症和免疫相关疾病研究中的一个重要分子靶点，并且是临床治疗多种疾病的潜在标志物和治疗靶点 。
热销产品
Recombinant Human Interleukin-1 alpha (IL1A) (CSB-YP011613HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA584603(IL1A Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA584603(IL1A Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA584603(IL1A Antibody) at dilution 1/666, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
Human Interleukin 1α,IL-1α ELISA Kit (CSB-E04620h)
验证数据
货号：CSB-E04620h
规格：96T/48T
灵敏度：7.8 pg/mL
检测范围：31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
Il1a Antibodies
Il1a for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA06565A0Rb | IL1A Antibody | Human | ELISA |
| CSB-PA06565C0Rb | IL1A Antibody, FITC conjugated | Human | |
| CSB-PA011613GA01HU | IL1A Antibody | Human | ELISA,WB |
| CSB-PA009537 | IL1A Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA107052 | IL1A Antibody | Human | ELISA,IHC |
| CSB-PA584603 | IL1A Antibody | Human | ELISA,WB,IHC |
Il1a for Macaca mulatta
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA011613LA01MOW | IL1A Antibody | Macaca mulatta, Human | ELISA, WB |
Il1a Proteins
Il1a Proteins for Capra hircus (Goat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613GO CSB-EP011613GO CSB-BP011613GO CSB-MP011613GO CSB-EP011613GO-B |
Recombinant Goat Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613PI CSB-EP011613PI CSB-BP011613PI CSB-MP011613PI CSB-EP011613PI-B |
Recombinant Pig Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613MOW | Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) | Yeast |
| CSB-AP003071MOW | Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) (Active) | E.Coli |
| CSB-EP011613MOW | Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) | E.coli |
| CSB-BP011613MOW CSB-MP011613MOW CSB-EP011613MOW-B |
Recombinant Macaca mulatta Interleukin-1 alpha (IL1A) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613MO CSB-EP011613MO CSB-BP011613MO CSB-MP011613MO CSB-EP011613MO-B |
Recombinant Mouse Interleukin-1 alpha (Il1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003251MO | Recombinant Mouse Interleukin-1 alpha protein (Il1a) | E.Coli |
| CSB-AP004721MO | Recombinant Mouse Interleukin-1 alpha (Il1a) (Active) | E.coli |
Il1a Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613HU | Recombinant Human Interleukin-1 alpha (IL1A) | Yeast |
| CSB-EP011613HUe0 | Recombinant Human Interleukin-1 alpha (IL1A) | E.coli |
| CSB-EP011613HU | Recombinant Human Interleukin-1 alpha (IL1A) | E.coli |
| CSB-AP001661HU | Recombinant Human Interleukin-1 alpha protein (IL1A) | E.Coli |
| CSB-BP011613HU CSB-MP011613HU |
Recombinant Human Interleukin-1 alpha (IL1A) | Baculovirus Mammalian cell |
| CSB-YP011613HUc7 | Recombinant Human Interleukin-1 alpha (IL1A) | Yeast |
| CSB-AP004261HU | Recombinant Human Interleukin-1 alpha (IL1A) (Active) | E.coli |
| CSB-AP005801HU | Recombinant Human Interleukin-1 alpha (IL1A) (Active) (GMP) | E.Coli |
| CSB-EP011613HU-B | Recombinant Human Interleukin-1 alpha (IL1A),Biotinylated | E.coli |
Il1a Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613BO CSB-EP011613BO CSB-BP011613BO CSB-MP011613BO CSB-EP011613BO-B |
Recombinant Bovine Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613RB CSB-EP011613RB CSB-BP011613RB CSB-MP011613RB CSB-EP011613RB-B |
Recombinant Rabbit Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613CA CSB-EP011613CA CSB-BP011613CA CSB-MP011613CA CSB-EP011613CA-B |
Recombinant Cat Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613DO CSB-EP011613DO CSB-BP011613DO CSB-MP011613DO CSB-EP011613DO-B |
Recombinant Dog Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-BP011613MOV CSB-MP011613MOV CSB-EP011613MOV-B |
Recombinant Macaca fascicularis Interleukin-1 alpha (IL1A) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613RA CSB-EP011613RA CSB-BP011613RA CSB-MP011613RA CSB-EP011613RA-B |
Recombinant Rat Interleukin-1 alpha (Il1a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011613DRI CSB-EP011613DRI CSB-BP011613DRI CSB-MP011613DRI CSB-EP011613DRI-B |
Recombinant Cercocebus atys Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP630687SH CSB-EP630687SH CSB-BP630687SH CSB-MP630687SH CSB-EP630687SH-B |
Recombinant Sheep Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP636720HO CSB-EP636720HO CSB-BP636720HO CSB-MP636720HO CSB-EP636720HO-B |
Recombinant Horse Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP661675BAAW CSB-EP661675BAAW CSB-BP661675BAAW CSB-MP661675BAAW CSB-EP661675BAAW-B |
Recombinant Bubalus carabanensis Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP733672GU CSB-EP733672GU CSB-BP733672GU CSB-MP733672GU CSB-EP733672GU-B |
Recombinant Guinea pig Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a Proteins for Lama glama (Llama)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP774725LBS CSB-EP774725LBS CSB-BP774725LBS CSB-MP774725LBS CSB-EP774725LBS-B |
Recombinant Lama glama Interleukin-1 alpha (IL1A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il1a ELISA Kit
Il1a ELISA Kit for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12019B | Bovine Interleukin 1,IL-1 ELISA Kit | serum, plasma, tissue homogenates | 250 pg/mL |
Il1a ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E06896Rb | Rabbit Interleukin 1,IL-1 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
Il1a ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04620h | Human Interleukin 1α,IL-1α ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates, cell lysates | 7.8 pg/mL |
Il1a ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04621m | Mouse Interleukin 1α,IL-1α ELISA kit | serum, plasma, tissue homogenates | 0.58 pg/ml |
Il1a ELISA Kit for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09725p | Pig Interleukin 1α,IL-1α ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 6.25 pg/mL |
Il1a ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04622r | Rat Interleukin 1α,IL-1α ELISA kit | serum, plasma, tissue homogenates. | 19.5 pg/ml. |
Il1a ELISA Kit for Monkey
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E10041Mo | Monkey Interleukin-1 alpha (IL1A) ELISA kit | serum, plasma, tissue homogenates | 1.95 pg/mL |
