MOG
MOG,即髓鞘少突胶质细胞糖蛋白,别名BTN6、BTNL11、MGC26137、MOG AluA、MOG AluB等。是一种主要在中枢神经系统少突胶质细胞膜表面及髓鞘最外层表达的蛋白质,属于免疫球蛋白超家族成员之一。MOG抗体相关疾病(MOG-IgG associated disorders, MOGAD)是近年来新认识的免疫介导的中枢神经系统炎性脱髓鞘疾病,与多发性硬化(MS)和视神经脊髓炎谱系疾病(NMOSD)不同,它是一种独立的疾病实体。MOGAD的发病机制可能涉及MOG特异性T滤泡辅助细胞促进B细胞分化,产生大量MOG-IgG,这些抗体进入中枢神经系统后与MOG结合,通过补体和抗体途径介导细胞杀伤作用,导致少突胶质细胞损伤和脱髓鞘。MOGAD的临床表现多样,包括视神经炎、脑膜脑炎、脑干脑炎、脊髓炎等,儿童中较成人更常见,且预后相对较好。
热销产品
Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial (CSB-MP619083HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MOG Antibody (CSB-PA619083ESR2HU)
验证数据
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA619083ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA619083ESR2HU at dilution of 1:100
Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit (CSB-EL014709HU)
验证数据
货号:CSB-EL014709HU
规格:96T/48T
灵敏度:3.9 pg/mL
检测范围:15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MOG Antibodies
MOG for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA014709GA01HU | MOG Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA619083ESR2HU | MOG Antibody | Human | ELISA, IHC |
MOG Proteins
MOG Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP619083HU CSB-BP619083HU CSB-EP619083HU-B |
Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-EP619083HU | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | E.coli |
CSB-MP619083HU(A4) | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG)-VLPs, Fluorescent | Mammalian cell |
CSB-MP619083HU | Recombinant Human Myelin-oligodendrocyte glycoprotein (MOG), partial | Mammalian cell |
MOG ELISA Kit
MOG ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL014709HU | Human Myelin-oligodendrocyte glycoprotein(MOG) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |