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Nr1i2

孕烷 X 受体(PXR, NR1I2)是核受体超家族的原型成员。PXR可以被内生素和异生素激活。作为一种关键的外源性受体,PXR的细胞功能主要通过其与调节基因序列以配体依赖性方式结合来发挥。PXR的经典下游靶基因参与外源性反应,如解毒、代谢和炎症。新出现的证据还表明,PXR信号传导涉及与癌症密切相关的细胞凋亡、细胞周期停滞、增殖、血管生成和氧化应激过程。

Nr1i2 Antibodies

Nr1i2 for Homo sapiens (Human)

Nr1i2 Proteins

Nr1i2 Proteins for Homo sapiens (Human)

Nr1i2 Proteins for Mus musculus (Mouse)

Nr1i2 Proteins for Macaca mulatta (Rhesus macaque)

Nr1i2 Proteins for Rattus norvegicus (Rat)