TBC1D4
TBC1D4，即TBC1域家族成员4，别名TBC1D4、RAB7L1等。它是一种由TBC1D4基因编码的蛋白激酶，属于TBC1域蛋白家族成员之一，在多种组织中表达。TBC1D4的作用机制涉及G蛋白信号传导的调控，特别是通过其TBC结构域对Rab GTP酶的活性进行调节，影响细胞内囊泡运输和蛋白质的细胞内定位。TBC1D4参与了细胞内多种生理过程，包括内质网到高尔基体的蛋白质转运、细胞极性的建立、细胞迁移等。TBC1D4的功能异常与多种疾病有关，如神经退行性疾病、肿瘤等。研究表明，TBC1D4在肿瘤细胞中的异常表达可能与肿瘤的侵袭性和转移性有关，使其成为癌症治疗的潜在靶点。
热销产品
TBC1D4 Antibody (CSB-PA023218LA01HU)
验证数据
Immunohistochemistry analysis of human adrenal gland tissue using CSB-PA023218LA01HU at dilution of 1:100
Immunocytochemistry analysis of human kidney tissue using CSB-PA023218LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA023218LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
TBC1D4 Antibodies
TBC1D4 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA080083 | Phospho-TBC1D4 (T642) Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA080084 | TBC1D4 Antibody | Human,Mouse | IHC, IF, ELISA |
| CSB-PA182529 | TBC1D4 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA592036 | TBC1D4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA023218LA01HU | TBC1D4 Antibody | Human | ELISA, IHC, IF |
| CSB-PA023218LB01HU | TBC1D4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023218LC01HU | TBC1D4 Antibody, FITC conjugated | Human | |
| CSB-PA023218LD01HU | TBC1D4 Antibody, Biotin conjugated | Human | ELISA |
TBC1D4 Proteins
TBC1D4 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP023218HU CSB-EP023218HU CSB-BP023218HU CSB-MP023218HU CSB-EP023218HU-B |
Recombinant Human TBC1 domain family member 4 (TBC1D4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
